Results 11 to 20 of about 520,818 (100)

تأثیر دما بر ساختار فاکتور رشد شبه‌انسولینی (IGF-1) و مطالعه‌ای مبتنی بر شبیه‌سازی با روش‌های دینامیک مولکولی و محاسبات کامپیوتری [PDF]

open access: yesمجله دانشگاه علوم پزشکی سبزوار, 1970
زمینه و هدف: فاکتور رشد شبه‌انسولینی به‌طور طبیعی در سیستم عصبی مرکزی (CNS) موجود است و نقش مهمی در تکثیر و تمایز سلولی در طی رشد و بلوغ مغز دارد. این فاکتورها به‌همراه پروتئین‌های پیوند به آن‌ها و گیرنده‌هایشان در نواحی آسیب دیده‌ی مغز بیان می‌شوند که ...
ریحانه صباغ زاده
doaj  

Drug Delivery by Carbon Nano Carrier for Use as Capecitabine Drug Carrier: A QM/MM study [PDF]

open access: yesNanochemistry Research
The most important and common methods of cancer treatment are chemotherapy, surgery and radiotherapy. But these mentioned methods have important side effects such as intolerable toxicity, limited drug access to cancer cells, heterogeneous drug and ...
Fahimeh Najafi
doaj   +1 more source

Homogeneous earthquake catalogue for Northeast region of India using robust statistical approaches

open access: yesGeomatics, Natural Hazards & Risk, 2017
Regular seismic hazard assessment requires essentially an updated and refined homogenous earthquake catalogue for the study region. Here, we have compiled the earthquake data for Northeast region of India in a chronological order from International ...
Auchitya Kumar Pandey   +2 more
doaj   +1 more source

Partial Knowledge in Multiple-Choice Testing [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2011
The intent of this study was to discover the nature of (partial) knowledge as estimated by the multiple-choice (MC) test method. An MC test of vocabulary, including 20 items, was given to 10 participants.
Ali Asghar Rostami Abusaeedi
doaj  

Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer

open access: yesBMC Cancer, 2021
Background Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect circulating tumor-derived EVs (ctEVs) by mutant mRNA transcripts (EV ...
Silvia R. Vitale   +15 more
doaj   +1 more source

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

open access: yesNature Communications, 2021
Duration of infectious SARS-CoV-2 shedding is an important measure for improved disease control. Here, the authors use virus cultures of respiratory tract samples from COVID-19 patients and observe a median shedding duration of 8 days and a drop below 5%
Jeroen J. A. van Kampen   +24 more
doaj   +1 more source

محاسبات مکانیک مولکولی و بررسی تأثیر حلال بر اثرات محیطی و ترمودینامیکی آنزیم کولین استیل ترانسفراز [PDF]

open access: yesمجله دانشگاه علوم پزشکی سبزوار, 1970
چکیده زمینه و هدف: فعالیت استیل کولین و آنزیم استیل کولین ترانسفراز در بیماری آلزایمر بررسی و مشخص شده است. از این جهت، نقص آنها می‌تواند باعث کاهش حافظه و یادگیری شود. میدان‌های نیرو، بر ساختار کولین استیل ترانسفراز تأثیر دارند.
ریحانه صباغزاده
doaj  

Análise da Performance da Técnica MC/MC-CDMA

open access: yesTrends in Computational and Applied Mathematics, 2007
A técnica Multi Portadora / Multi Código CDMA (MC/MC-CDMA) é analisada através de uma comparação do desempenho entre as técnicas Multi Código CDMA e Multi Portadora CDMA.
A.S. Araújo, G.A. Carrijo, E.L. Flores
doaj   +1 more source

Effect of arthritic synovial fluids on the expression of immunomodulatory factors by mesenchymal stem cells: an explorative in-vitro study

open access: yesFrontiers in Immunology, 2012
Background: In diseased joints, the catabolic environment results in progressive joint damage. Mesenchymal stem cells (MSCs) can have immunomodulatory effect by secreting anti-inflammatory factors. To exert these effects, MSCs need to be triggered by pro-
Maarten J.C. Leijs   +8 more
doaj   +1 more source

Anatomical pathways involved in generating and sensing rhythmic whisker movements

open access: yesFrontiers in Integrative Neuroscience, 2011
The rodent whisker system is widely used as a model system for investigating sensorimotor integration, neural mechanisms of complex cognitive tasks, neural development, and robotics.
Laurens W.J. Bosman   +12 more
doaj   +1 more source

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