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The MCL apprehension sign: A novel test for MCL instability

Journal of Clinical Orthopaedics and Trauma, 2023
This study describes a new clinical sign to diagnose clinically relevant medial collateral ligament (MCL) injury and evaluates its use in diagnosis and planning treatment for MCL injuries.A total of 30 consecutive patients with suspected MCL injury, visiting the sports knee clinic were screened by the senior author and the knee fellow for any clinical ...
Pranshu, Agrawal, Rob, Gilbert
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MCL

Proceedings of the XIV Brazilian Symposium on Information Systems, 2018
Software measures are underused due to the difficulty of interpreting their results and associating them to software quality. Different environments, languages, and development methodologies require specific measures and range of values. Thus, this paper proposes MCL (Metrics-based Constraint Language), a language that allows to specify, for different ...
Christian Marlon Souza Couto   +3 more
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Technique Corner: MCL

2021
Medial collateral ligament and posteromedial corner knee injuries are among the most frequently diagnosed conditions in sports medicine. These injuries can cause medial knee pain, side-to-side instability, and lead to secondary damage to both cruciate ligaments and articular cartilage.
Robert S. Dean   +4 more
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Unraveling MCL-1 degradation

Cell Death & Differentiation, 2006
Department of Biochemistry, St. Jude Children’s Research Hospital, Memphis,TN 38105, USA* Corresponding author: JT Opferman, Department of Biochemistry, St. JudeChildren’s Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.Tel: þ1-901-495-5524; Fax: þ1-901-525-8025;E-mail: joseph.opferman@stjude ...
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Anatomical MCL reconstruction following TKA

The Knee, 2016
Adequate ligament balancing has a tremendous impact on successful total knee arthroplasty. In case of instability, severely disabling symptoms require revision surgery. Here we present a case of early total knee arthroplasty failure due to secondary valgus laxity, which was successfully treated with medial collateral ligament (MCL) reconstruction.
Guido, Wierer   +4 more
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Treatment of MCL Injury in Combined ACL/MCL Injury

2017
Combined ACL and MCL injuries are the most common combined ligament injuries of the knee. Traditional management of isolated MCL injuries has been conservative. However, grade III MCL injuries or those associated with the PMC can lead to rotational laxity that can significantly impact patient functionality.
Daniel Whelan   +4 more
openaire   +1 more source

Smoking and Mouse MCL Healing

Journal of Knee Surgery, 2010
Cigarette smoking has been shown to delay soft tissue healing and complicate musculoskeletal recovery. Its deleterious effects have been proven in bone and soft tissue, although to a much more limited fashion in ligament or tendon. We exposed 120 experimental mice to two cigarettes per day for 2 months and then induced a blunt medial collateral ...
Rick, Wright   +3 more
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Treatment of relapsed/refractory MCL

Blood
Abstract Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin lymphoma that is clinically characterized by its heterogeneous behavior, with courses ranging from indolent to highly aggressive cases with limited prognosis.
Elisabeth Silkenstedt, Martin Dreyling
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Discovery of Hippo in MCL

Blood, 2010
In this issue of Blood , Hartmann and colleagues report on the results of a high-resolution genomic profiling study in a large series of MCL. Copy number alteration and expression data are amalgamated with clinical outcome. Their data confirm the critical role of the cell-cycle and DNA damage-
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Hitting the target in MCL

Blood, 2012
One of the major challenges in the evaluation of new therapies for lymphoma and other hematologic malignancies has been the ability to demonstrate changes in important biomarkers and pharmacodynamic end points in the tumor cell population.In this issue of Blood, Leonard et al provide an elegant evaluation of the cyclin-dependent kinase (cdk) inhibitor ...
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