Results 61 to 70 of about 66,016 (261)
Abstract Stener‐like distal injuries of the superficial medial collateral ligament (MCL) are characterized by displacement of the distal ligament stump superficial to the pes anserinus fascia, preventing anatomic healing and resulting in persistent valgus and anteromedial rotatory instability.
Logan D. Moews +6 more
wiley +1 more source
Abstract Medial meniscus posterior root tears frequently result in meniscal extrusion and disruption of normal tibiofemoral contact mechanics. Several techniques, including transtibial pullout and anchor‐based repair methods, are used for root repair and meniscus centralization.
Coşkun Genç +5 more
wiley +1 more source
Abstract Meniscal allograft transplant (MAT) is gaining popularity for treating meniscus deficiency. Various MAT techniques are described. Bony techniques such as bone plugs and bone slot techniques are considerably more technically challenging but show better reduction of extrusion than all‐soft‐tissue technique.
Sara N. Kiani +3 more
wiley +1 more source
Abstract Ramp lesions of the medial meniscus are frequently associated with anterior cruciate ligament injuries and contribute to persistent instability if untreated. Diagnosis is challenging, and repair techniques often require posteromedial portals or specialized devices.
Mohammad Ayati Firoozabadi +5 more
wiley +1 more source
Abstract This technical note describes a modified transtibial pullout repair for medial meniscus posterior root tear incorporating a barbed suture to improve fixation strength and load distribution. The technique combines 2 simple sutures placed near the torn root with a circumferential barbed suture passed through the posteromedial meniscocapsular ...
Nam Jun Baek +5 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
The adulthood of MRD detection in MCL
In this issue of Blood, Pott and colleagues correlate clinical outcome and MRD results in MCL.1 The analysis by real-time quantitative PCR of 259 patients included in 2 international randomized trials indicated MRD as an independent outcome predictor. The good large-scale applicability and high predictive value indicate that MRD detection is ready to ...
openaire +3 more sources
Model‐Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions
ABSTRACT Mechanistic models are central to quantitative understanding and optimization of Chinese hamster ovary (CHO) cell culture processes, but their utility is often restricted by parameter sets calibrated for specific cell lines, scales, or operating conditions.
Luxi Yu +2 more
wiley +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source

