Results 151 to 160 of about 163,984 (309)

Neoadjuvant camrelizumab combined with metronomic chemotherapy in patients with advanced esophageal squamous cell carcinoma: a pilot randomized phase 2 trial. [PDF]

BMC Med
Chen Z, Li W, Guo Y, Zhu Y, Song Y, Wu J, Zheng W, Tseng Y, Lin L, Tang F, Mao B, Zhao P, Guo X, Fu S, Chen G, Wu N, Lv B, Liu Y, Zhao S, Mo S, Ma K, Fu K, Zhang H, Zhang J, Luo F, Luo Z, Liu J.   +26 more
europepmc   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

PERMEPSY: a multicentre, randomized, double-blind proof-of-concept trial of personalized metacognitive training for adults with psychosis - a study protocol. [PDF]

Front Psychiatry
Lamarca M, Requejo C, Aleksandrowicz A, Goncalves A, Kreżołek M, Gelner H, Piwińska J, Fischer R, Schlechte M, Cavieres A, Acuña V, Berna F, Moritz S, König C, Gawęda Ł, Ochoa S.   +15 more
europepmc   +1 more source

Synergetic Combination of Carbon Xerogels, Graphene Oxide and nano‐ZnO for Aqueous and Organic Supercapacitors

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
This work proposes the synthesis of carbon‐based nanostructured materials obtained using ZnO as both nanos‐ template and catalysts simultaneously. During the synthesis, GO was used as a stabiliser, preventing the collapse of the 3D structure and improving its properties in terms of capacitance and surface area.
Rusbel Coneo‐Rodríguez, Alvaro Yamil Tesio, Fernando Pablo Cometto, Gustavo Marcelo Morales, Gabriel Ángel Planes, Alvaro Caballero   +5 more
wiley   +1 more source

Prognostic value of 3D mean CT attenuation in the solid component of resected part-solid lung adenocarcinomas. [PDF]

J Thorac Dis
Miyazaki R, Tamura M, Sakai T, Furukawa N, Bunno Y, Yamamoto M, Okada H.   +6 more
europepmc   +1 more source

ImS-MCTS: A New Importance Sampling MCTS Algorithm for Discrete Event System

With the emergence of a discrete event system (DES), the research community is developing in the direction of various issues within it. In this kind of system, the decision-making problem is one of the core issues. In this paper, we build a new decision-making algorithm ImS-MCTS based on Monte Carlo Tree Search (MCTS).
Ou, Tianxiang, Lu, Yanan, Wang, Yupeng, Wu, Xuesong, Cao, Jianwen   +4 more
openaire   +1 more source

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, EarlyView.
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Medium-Chain Triglycerides: Scientific and Regulatory Perspectives from Germany and Japan with a US Context-A Concise Review. [PDF]

Nutrients
Heidt C, Oertling H, Abramowicz M, Otsubo Y, Tokunaga S, Tsujino S.   +5 more
europepmc   +1 more source

OASIS3-MCT User Guide, OASIS3-MCT 5.0

, 2021
Valcke, S., Craig, Anthony, Maisonnave, Éric, Coquart, Laure   +3 more
openaire   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source