Results 81 to 90 of about 106,858 (296)

The oncogene Mct-1 promotes progression of hepatocellular carcinoma via enhancement of Yap-mediated cell proliferation

open access: yesCell Death Discovery, 2021
Malignant T-cell-amplified sequence 1 (Mct-1) has been reported as an oncogene in multiple malignant diseases. However, the function of Mct-1 in hepatocellular carcinoma (HCC) and the molecular mechanisms underlying tumor progression have not been ...
Wenjie Yang   +8 more
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

Sistemas de informação e linguagens documentárias no contexto dos regimes de informação: um exercício conceitual

open access: yesRDBCI: Revista Digital de Biblioteconomia e Ciência da Informação, 2006
O artigo apresenta o conceito de regime de informação aos gestores de informação, como contribuição aos processos de adaptação e adequação de sistemas de informação e linguagens documentárias para atender às necessidades informacionais dos usuários ...
Roberto J.G. Unger, Isa Maria Freire
doaj   +1 more source

The COSMO-CLM 4.8 regional climate model coupled to regional ocean, land surface and global earth system models using OASIS3-MCT: description and performance

open access: yes, 2017
. We developed a coupled regional climate system model based on the CCLM regional climate model. Within this model system, using OASIS3-MCT as a coupler, CCLM can be coupled to two land surface models (the Community Land Model (CLM) and VEG3D), the NEMO ...
A. Will   +8 more
semanticscholar   +1 more source

Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer

open access: yesCancer & Metabolism, 2016
There is increasing evidence that oncogenic Wnt signaling directs metabolic reprogramming of cancer cells to favor aerobic glycolysis or Warburg metabolism.
Stephanie Sprowl-Tanio   +8 more
semanticscholar   +1 more source

Effect of A223 administration on miRNA expression in MCT PAH.

open access: yes, 2016
Expression levels of miR-223 relative to saline-saline (naïve) control animals. (A) Lungs. (B) PA. (C) RV. (D) Plasma.—Saline-saline control reference line.
Igor B. Gubrij (555422)   +3 more
core   +1 more source

Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2

open access: yesAdvanced Science, EarlyView.
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim   +13 more
wiley   +1 more source

Benefits of monitoring patients with mobile cardiac telemetry (MCT) compared with the Event or Holter monitors

open access: yes, 2013
Jean-Patrick Tsang, Shunmugam Mohan Bayser Consulting, Skokie, IL, USA Introduction: This research is meant to establish if a patient monitored with mobile cardiac telemetry (MCT) sees different outcomes regarding diagnostic yield of arrhythmia ...
Mohan S, Tsang JP
core  

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity [PDF]

open access: yes, 2014
[[abstract]]Overexpression of Shc adaptor proteins is associated with mitogenesis, carcinogenesis and metastasis. Multiple copies in T-cell malignancy 1 (MCT-1) oncoprotein promotes cell proliferation, survival and tumorigenic effects.
Hung-Ju Shih;Hsiao-Huei Chen;Yen-An Chen;Meng-Hsun Wu;Gan-Guang Liou;Wei-Wen Chang;Linyi Chen;Lu-Hai Wang;Hsin-Ling Hsu
core  

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

open access: yesAdvanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun   +10 more
wiley   +1 more source

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