Results 51 to 60 of about 166,374 (227)

Defining Optimally Safe and Effective Blood Levels of Hydroxychloroquine in Lupus: An Important Step toward Precision Drug Monitoring

Arthritis &Rheumatology, Accepted Article.
Background Using hydroxychloroquine (HCQ) dose of 5 mg/kg/day in systemic lupus erythematosus (SLE) is associated with a higher risk of flares; HCQ blood level monitoring could be a better way to adjust HCQ dose. We studied the upper threshold for a reference range of HCQ levels to inform routine monitoring.
Shivani Garg, Benoît Blanchet, Yann Nguyen, Fauzia Hollnagel, Ada Clarke, Michelle Petri, Murray B. Urowitz, John G. Hanly, Caroline Gordon, Sang‐Cheol Bae, Juanita Romero‐Diaz, Jorge Sanchez‐Guerrero, Ann E. Clarke, Sasha Bernatsky, Daniel J. Wallace, David A. Isenberg, Anisur Rahman, Joan T. Merrill, Paul R. Fortin, Dafna D. Gladman, Ian N. Bruce, Ellen M. Ginzler, Mary Anne Dooley, Rosalind Ramsey‐Goldman, Susan Manzi, Andreas Jönsen, Graciela S. Alarcón, Ronald F. Van Vollenhoven, Cynthia Aranow, Véronique Le Guern, Meggan Mackay, Guillermo Ruiz‐Irastorza, S. Sam Lim, Murat Inanc, Kenneth C. Kalunian, Søren Jacobsen, Christine A. Peschken, Diane L. Kamen, Anca Askanase, Jill Buyon, Julie Chezel, Alicja Puszkiel, Nathalie Costedoat‐Chalumeau   +42 more
wiley   +1 more source

IS COMMON CAROTID INTIMA MEDIA THICKNESS AN INDEPENDENT PREDICTOR FOR CORONARY ARTERY DISEASE

ARYA Atherosclerosis, 2010
Introduction: Non-invasive measurement of carotid intima media thickness (IMT) has been noted as a marker for atherosclerosis and can serve as a predictor of cardiovascular accidents.
Masoume Sadeghi, Hamidreza Roohafza, Masoud Poormoghadas, Aliakbar Tavasoli, Ramin Heidari   +4 more
doaj  

Targeting depletion of myeloid-derived suppressor cells potentiates PD-L1 blockade efficacy in gastric and colon cancers

OncoImmunology, 2022
Myeloid-derived suppressor cells (MDSCs) have been demonstrated to suppress antitumor immunity and induce resistance to PD-1/PD-L1 blockade immunotherapy in gastric and colon cancer patients.
Yao Tang, Cong Zhou, Qingli Li, Xiaojiao Cheng, Tinglei Huang, Fuli Li, Lina He, Baiweng Zhang, Shuiping Tu   +8 more
doaj   +1 more source

Message authentication codes for the Network Time Protocol [PDF]

, 2018
RFC 5905 [RFC5905] states that Network Time Protocol (NTP) packets should be authenticated by appending a 128-bit key to the NTP data, and hashing the result with MD5 to obtain a 128-bit tag. This document deprecates MD5-based authentication,
Goldberg, Sharon, Malhotra, Aanchal
core  

Automatically Mining Program Build Information via Signature Matching

, 2013
Program build information, such as compilers and libraries used, is vitally important in an auditing and benchmarking framework for HPC systems. We have developed a tool to automatically extract this information using signature-based detection, a common ...
Lu, Charng-Da
core   +1 more source

Building a Sustainable Manufacturing Industry: The Role of Innovativeness and Other Strategic Factors

Business Strategy and the Environment, EarlyView.
ABSTRACT Sustainable manufacturing is an effective way to improve organizational performance. In this sense, this research aims to analyze the determining factors of the success of the Brazilian manufacturing industry and evaluate innovativeness (Innovation Capacity) as a central point of sustainable manufacturing.
Julio Cesar Ferro De Guimarães, Eric Charles Henri Dorion, Eliana Andrea Severo, Bruna Lorena de Lima Dantas, Marcela Rebecca Pereira, Joyce Soares Da Silva   +5 more
wiley   +1 more source

Enhancing the Security of Customer Data in Cloud Environments Using a Novel Digital Fingerprinting Technique

International Journal of Digital Multimedia Broadcasting, 2016
With the rapid rise of the Internet and electronics in people’s life, the data related to it has also undergone a mammoth increase in magnitude. The data which is stored in the cloud can be sensitive and at times needs a proper file storage system with a
Nithya Chidambaram, Pethuru Raj, K. Thenmozhi, Rengarajan Amirtharajan   +3 more
doaj   +1 more source

Cryptography: Perancangan Middleware Web Service Encryptor menggunakan Triple Key MD5. Base64, dan AES

Jurnal Tekno Insentif, 2021
Penelitian ini membantu dalam melalukan proses Keamanan data atau informasi untuk menjamin kerahasiaan dan keaslian data atau informasi. Dalam perancangan ini menggunakan Kriptografi sebagai salah satu solusi dalam mengamankan data atau informasi. Metode
Maulyanda Az, Syafrial Fachri Pane, Rolly Maulana Awangga   +2 more
doaj   +1 more source

Prognostic value of NT‐proBNP in patients with primary mitral regurgitation undergoing transcatheter edge‐to‐edge repair

European Journal of Heart Failure, EarlyView.
In the PRIME‐MR study, patients with higher N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) tertiles more frequently reached death or heart failure hospitalization (HFH) within 3 years. Log‐transformed NT‐proBNP levels independently predicted the primary endpoint (adjusted hazard ratio 1.17, 95% confidence interval 1.07–1.28; p < 0.001).
Philipp von Stein, Jessica Weimann, Roman Pfister, Sebastian Ludwig, Benedikt Koell, Erwan Donal, Dhairya Patel, Lukas Stolz, Tetsu Tanaka, Andrea Scotti, Teresa Trenkwalder, Felix Rudolph, Daryoush Samim, Cristina Giannini, Julien Dreyfus, Jean‐Michel Paradis, Marianna Adamo, Nicole Karam, Yohann Bohbot, Anne Bernard, Bruno Melica, Angelo Quagliana, Yoan Lavie Badie, Mirjam Kessler, Omar Chehab, Simon Redwood, Edith Lubos, Lars Sondergaard, Marco Metra, Chiara Primerano, Fabien Praz, Muhammed Gerçek, Erion Xhepa, Georg Nickenig, Azeem Latib, Niklas Schofer, Raj Makkar, Juan F. Granada, Thomas Modine, Jörg Hausleiter, Augustin Coisne, Daniel Kalbacher, Christos Iliadis, on behalf of the PRIME‐MR Investigators, Paul Achouh, David Attias, Stephan Baldus, Alain Berrebi, Guillaume Bonnet, Laura Granada, Frederic Bouisset, Corentin Bourg, Thierry Bourguignon, Diogo Ferreira, Stéphane Lafitte, Thibault Lhermusier, Guillaume L'official, Mohammed Nejjari, Edoardo Pancaldi, Lydia X. Plewe, Tobias Rheude, Natacha Rousse, Volker Rudolph, Dan Rusinaru, Christophe Saint‐Etienne, Francisco Sampaio, Jury Schewel, Arnaud Sudre, Christophe Tribouilloy, Marcel Weber, Stephan Windecker   +70 more
wiley   +1 more source

Serious Illness Conversation in the Care of Atypical Parkinsonian Disorders: A Practical Guide for Neurology Clinicians

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Compared to Parkinson's disease, atypical parkinsonian disorders (APD) are characterized by a more rapidly progressive course, often leading to profound disability. Effective communication between clinicians, patients, and care partners is essential to support patient‐centered care and shared decision‐making.
Michiko K. Bruno, Jocelyn Jiao, Neha M. Kramer, Margaret Ivancic, Claudia Chou, Jessica Shurer, Thomas Carroll, on behalf of CurePSP Centers of Care Palliative Care Working Group   +7 more
wiley   +1 more source