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Genome-Wide CRISPR Screens Identify ABCG2-Mediated Drug Resistance to the Threonine Tyrosine Kinase (TTK) Inhibitor CFI-402257 in Breast Cancer. [PDF]

open access: yesInt J Mol Sci
Thu KL   +13 more
europepmc   +1 more source
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MDA for random forests: inconsistency, and a practical solution via the Sobol-MDA

Biometrika, 2021
Variable importance measures are the main tools used to analyse the black-box mechanisms of random forests. Although the mean decrease accuracy is widely accepted as the most efficient variable importance measure for random forests, little is known ...
Cl'ement B'enard   +2 more
semanticscholar   +1 more source

MDA-GCNFTG: identifying miRNA-disease associations based on graph convolutional networks via graph sampling through the feature and topology graph

Briefings Bioinform., 2021
Accurate identification of the miRNA-disease associations (MDAs) helps to understand the etiology and mechanisms of various diseases. However, the experimental methods are costly and time-consuming.
Yanyi Chu   +10 more
semanticscholar   +1 more source

The Best Way to Select Features? Comparing MDA, LIME, and SHAP

The Journal of Financial Data Science, 2020
Feature selection in machine learning is subject to the intrinsic randomness of the feature selection algorithms (e.g., random permutations during MDA).
Xin Man, Ernest P. Chan
semanticscholar   +1 more source

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