Results 191 to 200 of about 31,132 (248)

Determining MCID threshold for Knee Society Score to assess patient satisfaction in knee arthroplasty. [PDF]

NPJ Digit Med
Wang W, Wen C.
europepmc   +1 more source

Nanoparticle‐Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This study presents a nanoparticle‐embedded nanofiber (5F/STFM/R‐ES) to inhibit melanoma growth and reduce the risk of metastasis and recurrence. The drug delivery system induces ferroptosis and potentiates immunotherapy through resiquimod (R848) and Fe/Mn‐based metal‐polyphenol networks (TFM).
Mingyang Li, Rongrong Li, Baotong Xu, Yuhan Lian, Chenyu Yang, Jingwen Li, Junhao Liang, Linhan Ding, Dongsheng Zhang, Jing Guo, Xiao Fu   +10 more
wiley   +1 more source

A biomimetic model composed of injectable 3D muscle-like tissue, stromal and immune cells for recapitulating the rapid immune signature predictive of mRNA vaccine immunogenicity. [PDF]

Front Immunol
Etna MP, Fuoco C, Severa M, Ricci D, Sinigaglia A, Lucca C, Cairo G, Bottazzi B, Garlanda C, Palamara AT, Barzon L, Gargioli C, Coccia EM.   +12 more
europepmc   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

Advanced Science, Volume 13, Issue 1, 5 January 2026.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo, Kunzhao Huang, Xiaoyuan Yi, Pei Lu, Huaying Xie, Wen Li, Qingyu Zeng, Feifei He, Duo Wang, Liyan Wang   +9 more
wiley   +1 more source

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

Reliability of Different Dynamometers Used to Measure Isometric Shoulder Strength: A Comparative Study of Two Dynamometers in 526 Adults. [PDF]

Cureus
Loske S, Carlisle E, Strauss R, Walsh E, Gore A, Sullivan D, Duke P, Ross M.   +7 more
europepmc   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 46-62, January 2026.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

Test-retest reliability and minimal detectable change of Dutch-Flemish Patient Reported Outcomes Measurement Information System (PROMIS®) Computerized Adaptive Tests for musculoskeletal disorders. [PDF]

PLoS One
Arensman RM, Haan EJA, Terwee CB, van Rosmalen J, Wittink H, Kiers H.   +5 more
europepmc   +1 more source

Reliability Analysis of In-person and Virtual Goniometric Measurements for Select Shoulder and Forearm Motions. [PDF]

Int J Sports Phys Ther
Whitson A, Cook T, Middleton L, Humphrey C, Sciascia A.   +4 more
europepmc   +1 more source

SAMOS Air‐Sea Fluxes: 2005–2024

Geoscience Data Journal, Volume 13, Issue 1, January 2026.
The MarineFlux project created a dataset of air/sea turbulent fluxes for 2005–2024 using three bulk flux algorithms and input data from a collection of research vessels contributing to the Shipboard Automated Meteorological and Oceanographic Systems (SAMOS) initiative.
Marc Castells, Shawn R. Smith, Amanda Lovett, Mark A. Bourassa   +3 more
wiley   +1 more source