Results 61 to 70 of about 31,132 (248)

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Maximal Rashba Splitting in GeTe/Bi2Te3 Heterostructures via Strong Band Bending

Advanced Science, EarlyView.
An unprecedented strength of Rashba effect with ER = 0.57 eV, k0=0.16Å−1$\;{k_0} = 0.16\;{\mathrm{\AA}^{ - 1}}$ and αR=6.86eV·Å$ {\alpha _{\mathrm{R}}} = 6.86{\mathrm{\;eV}} \cdot {\mathrm{\AA}}$ in GeTe (1 nm)/Bi2Te3 (1 QL) heterostructure. The enhanced Rashba is origined from the band bending effect in the heterojunction region of GeTe /Bi2Te3 ...
Qing‐Lin Yang, Xu Yang, Jia‐Wan Li, Yan Li, Jin Tang, Hai‐Feng Du, Zi‐Zhao Gong, Hao‐Pu Xue, Jia‐Nan Liu, Zhuo Deng, Peng‐Tao Yang, Xiang‐Qun Zhang, Wei He, Yusheng Hou, Zhao‐Hua Cheng   +14 more
wiley   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

d‐Wave Fermi Surface Instability in the Nematic Phase of Two Monolayer FeSe/SrTiO3

Advanced Science, EarlyView.
Angle‐resolved photoemission spectroscopy reveals a d‐wave nematic order in two‐monolayer FeSe/SrTiO3, showing degenerate dxz/dyz bands at Γ but a pronounced splitting at M. This momentum‐dependent anisotropy identifies the nematicity as a d‐wave Fermi surface (Pomeranchuk) instability, highlighting 2D FeSe as a model platform to explore the interplay ...
C. Y. Tang, X.‐L. Peng, Y.‐H. Yuan, P. Zhang, G.‐N. Phan, S.‐Y. Gao, Y.‐B. Huang, L.‐Y. Kong, T. Qian, W. Li, Q.‐K. Xue, Z.‐Q. Wang, K. Jiang, Y.‐J. Sun, H. Ding   +14 more
wiley   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Effectiveness of a thoracic multidisciplinary clinic in the treatment of stage III non-small-cell lung cancer

Journal of Multidisciplinary Healthcare, 2016
Eliot L Friedman,1 Robert J Kruklitis,2 Brian J Patson,1 Dennis M Sopka,3 Michael J Weiss4 1Division of Hematology-Medical Oncology, 2Division of Pulmonary and Critical Care Medicine, 3Department of Radiation Oncology, 4Health Systems Research and ...
Friedman EL, Kruklitis RJ, Patson BJ, Sopka DM, Weiss MJ   +4 more
doaj  

Performance of an Idiopathic Pulmonary Fibrosis Derived Multibiomarker Panel for Rheumatoid Arthritis‐Associated Interstitial Lung Disease

Arthritis &Rheumatology, Accepted Article.
Objective To assess whether a panel of peripheral blood biomarkers associated with idiopathic pulmonary fibrosis (IPF) is also associated with interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) utilizing three independent cohorts.
Brent A. Luedders, Daniel Kass, Joshua F. Baker, Michael J. Duryee, Yangyuna Yang, Punyasha Roul, Halie Frideres, Katherine D. Wysham, Paul A. Monach, Andreas Reimold, Gail S. Kerr, Gary Kunkel, Grant W. Cannon, Scott M. Matson, Jill A. Poole, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England, Dana P. Ascherman   +18 more
wiley   +1 more source

Platelet concentrates modulate myeloid dendritic cell immune responses

Platelets, 2018
Platelet transfusion has been reported to modulate the recipients’ immune system. To date, the precise mechanism(s) driving poor patient outcomes (e.g., increased rate of mortality, morbidity, infectious complications and prolonged hospital stays ...
Katrina K. Ki, Helen M. Faddy, Robert L. Flower, Melinda M. Dean   +3 more
doaj   +1 more source

Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras, Abdelrahman G. Tawfik, Guilherme Del Fiol, Kensaku Kawamoto, Thomas Reese, Katy Trinkley, Aubrey Jones, James Mitchell, Daniel C. Malone   +8 more
wiley   +1 more source