Results 231 to 240 of about 40,945 (273)
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Immunomodulating Activity of MDMA
Annals of the New York Academy of Sciences, 2000AbstractMDMA (3,4‐methylenedioxymethamphetamine) use can cause neurochemical, behavioral and endocrine alterations, similar to those produced by exposure to acute stress, suggesting its potential as a “chemical stressor.” It is known that stressful stimuli can produce a depression of immune function and an alteration in immune cells distribution.In ...
R, Pacifici +10 more
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(±)-MDMA and its enantiomers: potential therapeutic advantages of R(−)-MDMA
Psychopharmacology, 2017The use of (±)-3,4-methylenedioxymethamphetamine ((±)-MDMA) as an adjunct to psychotherapy in the treatment of psychiatric and behavioral disorders dates back over 50 years. Only in recent years have controlled and peer-reviewed preclinical and clinical studies lent support to (±)-MDMA's hypothesized clinical utility. However, the clinical utility of (±
Elizabeth G, Pitts +4 more
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Increased responsiveness to MDMA in adult rats treated neonatally with MDMA
Neurotoxicology and Teratology, 2006MDMA [(+/-)3,4-methylenedioxymethamphetamine, also known as ecstasy] is a popular recreational drug among women of reproductive age. The objective of this study was to investigate the long-term neurobehavioral consequences of early developmental MDMA exposure. On postnatal days (PD) 1-4, Sprague-Dawley rats received two 10 mg/kg injections of MDMA with
Brian J, Piper, Jerrold S, Meyer
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The subjective effects of MDMA and mCPP in moderate MDMA users
Drug and Alcohol Dependence, 2001The present study is part of a research program designed to better understand the neurochemical mechanisms underlying the abuse liability of 3,4-methylenedioxymethamphetamine (MDMA) in humans. In these studies, MDMA will be compared to prototypical dopamine (D-amphetamine) and serotonin (meta-chlorophenylpiperazine, mCPP) releasing agents on a variety ...
M E, Tancer, C E, Johanson
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New England Journal of Medicine, 2003
To the Editor: Recreational use of 3,4-methylenedioxymethamphetamine (MDMA), or “ecstasy,” has been increasing.
Sandra M. Kuniyoshi, Joseph Jankovic
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To the Editor: Recreational use of 3,4-methylenedioxymethamphetamine (MDMA), or “ecstasy,” has been increasing.
Sandra M. Kuniyoshi, Joseph Jankovic
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Discriminative profile of MDMA
Pharmacology Biochemistry and Behavior, 1986Groups of rats were trained to discriminate the stimulus properties of dopaminergically and/or serotonergically active drugs, viz., apomorphine, fenfluramine, tetrahydro-beta-carboline (THBC) and l-cathinone. Once trained, these animals were given several doses of drugs used in training and dose-response relationships and ED50 values were generated ...
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Nervenheilkunde
ZUSAMMENFASSUNGNeben den klassischen Psychedelika, z. B. Psilocybin, werden wieder vermehrt andere Substanzen wie 3,4-Methylendioxy-N-methylamphetamin (MDMA) erforscht. Das Entaktogen („innerlich berührend“) ist in den USA nur noch wenige Schritte von einer möglichen Zulassung zur Behandlung der posttraumatischen Belastungsstörung entfernt.
Laura Bechtold, Dimitris Repantis
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ZUSAMMENFASSUNGNeben den klassischen Psychedelika, z. B. Psilocybin, werden wieder vermehrt andere Substanzen wie 3,4-Methylendioxy-N-methylamphetamin (MDMA) erforscht. Das Entaktogen („innerlich berührend“) ist in den USA nur noch wenige Schritte von einer möglichen Zulassung zur Behandlung der posttraumatischen Belastungsstörung entfernt.
Laura Bechtold, Dimitris Repantis
openaire +1 more source