Results 1 to 10 of about 1,211 (78)

N-Methyl-3,4-methylenedioxyamphetamine-induced hepatotoxicity in rats: Oxidative stress after acute and chronic administration [PDF]

open access: yesVojnosanitetski Pregled, 2004
Background. The underlying mechanisms of N-Methyl-3,4-methylenedioxyamphetamine-MDMA-induced hepatotoxicity are still unknown. The aim of this study was to evaluate hepatic oxido-reductive status in the rats liver after the single and repeated ...
Ninković Milica   +4 more
doaj   +5 more sources

MDMA (N-methyl-3,4-methylenedioxyamphetamine) and its stereoisomers: Similarities and differences in behavioral effects in an automated activity apparatus in mice [PDF]

open access: yesPharmacology Biochemistry and Behavior, 2008
Racemic MDMA (0.3-30 mg/kg), S(+)-MDMA (0.3-30 mg/kg), R(-)-MDMA (0.3-50 mg/kg) and saline vehicle (10 ml/kg) were comprehensively evaluated in fully automated and computer-integrated activity chambers, which were designed for mice, and provided a detailed analysis of the frequency, location, and/or duration of 18 different activities.
Richard, Young, Richard A, Glennon
openaire   +3 more sources

From Efficacy to Effectiveness: Evaluating Psychedelic Randomized Controlled Trials for Trustworthy Evidence‐Based Policy and Practice [PDF]

open access: yesPharmacology Research & Perspectives
The recent review of a new drug application for MDMA‐assisted therapy for posttraumatic stress disorder by the United States' Food and Drug Administration (FDA) highlighted epistemological and methodological challenges for evidence assessments.
Eduardo Ekman Schenberg
doaj   +2 more sources

The Effects of Folic Acid on Testicular Histology, Sperm Quality, and Spermatogenesis Indices Following 3,4-Methylenedioxymethamphetamine Exposure in Adult Male Rats [PDF]

open access: yesAddiction and Health, 2021
Background: There is an increasing concern over acute exposure of amphetamine and its derivative such as3,4-methylenedioxymethamphetamine (MDMA) on male reproductive toxicity. Supplementary vitamins canreduce the oxidative stresses and repair the damages
Iman Rad   +6 more
doaj   +1 more source

Entactogens: How the Name for a Novel Class of Psychoactive Agents Originated

open access: yesFrontiers in Psychiatry, 2022
At first glance, it appears there is little difference between the molecular structures of methylenedioxymethamphetamine (MDMA), which has an N-methyl attached to its amino group, and methylenedioxyamphetamine (MDA), a primary amine that is recognized to
David E. Nichols
doaj   +1 more source

Ecstasy tablets intoxication with lethal autcome [PDF]

open access: yesVojnosanitetski Pregled, 2007
Background. Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), is a synthetic compound increasingly popular as a recreational drug. Tablets known as ecstasy contain MDMA, but may also contain caffeine, ephedrine, paramethoxyamphetamine, 3,4 ...
Đorđević Snežana   +1 more
doaj   +1 more source

Polyacrylonitrile Nanofiber-Based Quartz Crystal Microbalance for Sensitive Detection of Safrole

open access: yesSensors, 2018
Safrole is the main precursor for producing the amphetamine-type stimulant (ATS) drug, N-methyl-3,4-methylenedioxyamphetamine (MDMA), also known as ecstasy.
Aditya Rianjanu   +6 more
doaj   +1 more source

Recurrent Syncope following Substance Abuse; a Case Report

open access: yesEmergency, 2016
Drug abuse is considered as the most common poisoning in the world. Stimulants agent especially amphetamines and methamphetamines are among important abused substances.
Forod Salehi   +3 more
doaj   +1 more source

Efeitos terapêuticos dos psicodélicos em doenças psiquiátricas: uma revisão integrativa

open access: yesBionorte, 2022
Objetivo: analisar a capacidade de atuação das drogas psicodélicas no sistema nervoso central, auxiliando no tratamento de doenças psiquiátricas. Materiais e Métodos: trata-se de revisão integrativa feita a partir de buscas nas bases de dados PubMed e ...
Karen Gonçalves Santos Ribeiro   +4 more
doaj  

HPLC Measurement of MDMA Content in Ecstasy Tablets Available in the Black Market of West Azerbaijan Province, Northwestern Iran [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Background:Ecstasy, mainly composed of 3,4-methylenedioxymethamphetamine (MDMA), is one of the most popular addictive synthetic drugs. This study was aimed to investigate the amount of MDMA in the ecstasy tablets seized in West Azerbaijan province ...
Reza Ghafari   +3 more
doaj  

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