Results 21 to 30 of about 13,980,406 (134)

Accumulation of neurotoxic thioether metabolites of 3,4-(±)-methylenedioxymethamphetamine in rat [PDF]

, 2008
The serotonergic neurotoxicity of 3,4-(Ϯ)-methylenedioxymethamphetamine (MDMA) appears dependent upon systemic metabolism because direct injection of MDMA into the brain fails to reproduce the neurotoxicity.
Serrine S Lau, Terrence J Monks, Gladys V Erives   +2 more
core  

Identification of synthetic precursors of amphetamine-like drugs using Raman spectroscopy and ab initio calculations: beta-Methyl-beta-nitrostyrene derivatives

, 2004
The present work reports a vibrational spectroscopic study of several beta-methyl-beta-nitrostyrene derivatives, which are important intermediates in the synthesis of illicit amphetamine-like drugs, such as 3,4-methylenedioxymethamphetamine (MDMA), 3,4 ...
Milhazes, Nuno, Calheiros, Rita, Borges, Fernanda, Marques, M. Paula M.   +3 more
core   +1 more source

Suitability of Electrochemical Sensing on Screen‐Printed Carbon Electrodes for the Identification of Eutylone (βk‐EBDB)

Electroanalysis, Volume 38, Issue 3, March 2026.
Voltammetric methods on screen‐printed carbon electrodes were employed for the rapid detection of the synthetic cathinone β‐keto‐ethylbenzodioxolylbutanamine (βk‐EBDB) in supporting electrolyte and human biological fluids. The electroanalytical method is promising as a portable drug testing device for on‐site applications—providing a repeatable linear ...
Harry Van Dorssen, Shanlin Fu, Morgan Alonzo   +2 more
wiley   +1 more source

2-Fluoro-N-methyl-N-({(3S,4S)-4-[2-(trifluoromethyl)phenoxy]-3,4-dihydro-1H-isochromen-3-yl}methyl)ethanamine

, 2015
Starting from N-methyl-1-{(3S,4S)-4-[2-(trifluoromethyl)phenoxy]-3,4-dihydro-1H-isochromen-3-yl}methanamine (1) target compound 2 is prepared using a mild, direct alkylation approach with 2-fluoroethyl ...
Holzer, Wolfgang, Neudorfer, Catharina, Karem Shanab, Wadsak, Wolfgang, Helmut Spreitzer, Catharina Neudorfer, Wolfgang Holzer, Rami-Mark, Christina, Christina Rami-Mark, Shanab, Karem, Markus Mitterhauser, Wolfgang Wadsak, Mitterhauser, Markus, Spreitzer, Helmut   +13 more
core   +2 more sources

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

N-(3,4-Dichlorophenyl)methyl Oxamic Acid

, 1997
A mixture of N-(3,4-dichlorophenyl)methyl oxamic acid ethyl ester [1] (7.609 g, 27.56 mmol), ethanol (400 ml), NaOH (1N, 32 ml) and water (200ml) was stirred at r.t.
Shu-Kun Lin
core   +1 more source

Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLC–MS/MS

Drug Testing and Analysis, Volume 17, Issue 10, Page 1877-1895, October 2025.
This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean‐up is obtained by parallel artificial liquid membrane extraction and analyzed by liquid chromatography–tandem mass spectrometry.
Martina Croce, Camilla Montesano, Ilenia Bracaglia, Francesco Bartolini, Marcello Mascini, Dario Compagnone, Manuel Sergi   +6 more
wiley   +1 more source

Recent Advances in Liquid Chromatography–Mass Spectrometry (LC–MS) Applications in Biological and Applied Sciences

Analytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Liquid chromatography–mass spectrometry (LC–MS) is a highly sophisticated analytical technique that has become indispensable for sample analysis across various scientific domains. In recent years, LC–MS has emerged as a cornerstone technology in comparative replicate sample analysis, particularly in the fields of proteomics, lipidomics and ...
Samyah Alanazi
wiley   +1 more source

TRICARBONYLCHROMIUM(0) PROMOTED STEREOSELECTIVE CYCLIZATIONS OF THE N-3,4-DIMETHOXYPHENETHYL DERIVATIVES OF THE 1-PHENYL ETHANOLAMINES HALOSTACHINE, EPHEDRINE AND PSEUDOEPHEDRINE TO 1-PHENYL-N-METHYL-7,8-DIMETHOXY-1,2,4,5-TETRAHYDROBENZAZEPINES

, 1990
Acid promoted cyclisation of homochiral (R)-N-(3,4-dimethoxyphenethyl)-halostachine proceeds with almost total racemisation to yield 1-phenyl-N-methyl-1,2,4,5-tetrahydrobenz[d]azepine (e.e. 6%).
Stephen G. Davies, Alan Naylor, David Middlemiss, Steven J. Coote   +3 more
core   +1 more source

2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine

, 2015
Starting from N-methyl-1-[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine (1) target compound 2 is prepared in a mild, direct alkylation approach with 2-fluoroethyl ...
Holzer, Wolfgang, Neudorfer, Catharina, Karem Shanab, Wadsak, Wolfgang, Helmut Spreitzer, Catharina Neudorfer, Wolfgang Holzer, Rami-Mark, Christina, Christina Rami-Mark, Shanab, Karem, Markus Mitterhauser, Wolfgang Wadsak, Mitterhauser, Markus, Spreitzer, Helmut   +13 more
core   +2 more sources