Results 31 to 40 of about 1,312 (139)

Health Benefits and Therapeutic Potential of Quercetin

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Psychedelic-assisted research for the treatment of drug and alcohol addiction : a scoping review [PDF]

open access: yes, 2022
This master thesis is written as a scoping review article supplemented with a “kappe” for more extensive information, detailed explanations, and supplementary data for the article.
Berg, Susanne Ranheim
core  

Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLC–MS/MS

open access: yesDrug Testing and Analysis, Volume 17, Issue 10, Page 1877-1895, October 2025.
This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean‐up is obtained by parallel artificial liquid membrane extraction and analyzed by liquid chromatography–tandem mass spectrometry.
Martina Croce   +6 more
wiley   +1 more source

The Mechanism of Calcium Handling Proteins and NF-κB in Calcium Dyshomeostasis of Cardiomyocytes Caused by Acute MDMA Exposure

open access: yesFayixue Zazhi
ObjectiveTo explore the mechanism of myocardial toxicity caused by N-methyl-3,4-methyle-nedioxyamphetamine (MDMA), the changes of intracellular calcium oscillation mode and calcium handling proteins during acute exposure to different concentrations of ...
WANG Rong-shuai   +8 more
doaj   +1 more source

Recent Advances in Liquid Chromatography–Mass Spectrometry (LC–MS) Applications in Biological and Applied Sciences

open access: yesAnalytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Liquid chromatography–mass spectrometry (LC–MS) is a highly sophisticated analytical technique that has become indispensable for sample analysis across various scientific domains. In recent years, LC–MS has emerged as a cornerstone technology in comparative replicate sample analysis, particularly in the fields of proteomics, lipidomics and ...
Samyah Alanazi
wiley   +1 more source

Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS

open access: yesDrug Testing and Analysis, Volume 17, Issue 6, Page 903-914, June 2025.
A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces   +5 more
wiley   +1 more source

Mechanistic Analysis of Repeated Dose Toxicity Studies [PDF]

open access: yes, 2023
Repeated dose toxicity studies in animals form the basis of chemical safety evaluations. Many parameters can be measured and analysed to assess the potential of the test chemical to cause adverse effects in the test animals and predict potential adverse ...
CHANDRASEKARAN Vidya   +6 more
core   +1 more source

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine‐Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
This study uses Caenorhabditis elegans to assess the activity of amphetamine‐type stimulants (ATS) and their analogs. The research highlights the roles of dopamine and serotonin pathways, distinguishes chiral forms of ATS, and identifies structure‐activity relationships. These findings provide a rapid and cost‐effective model for evaluating the effects
Yuanpeng Li   +3 more
wiley   +1 more source

Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning‐Based Advanced Perspectives

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim   +5 more
wiley   +1 more source

Density Functional Theory in Forensic Science: Applications and Challenges

open access: yesWIREs Forensic Science, Volume 7, Issue 1, March 2025.
DFT and other in silico methods are increasingly applied in forensic analysis. This review highlights the use of DFT in key areas such as new psychoactive substances, food adulteration, blood analysis, latent fingerprint detection, and explosives.
Lívia Salviano Mariotto   +4 more
wiley   +1 more source

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