Results 71 to 80 of about 1,592,361 (298)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

MDR codes and self-dual codes on Cartesian product codes

open access: yesTongxin xuebao, 2010
A Cartesian product code of the linear codes C1 , , C s in 1 , ,Z r Z rs was defined. According to the theorem of submodulo isomorphism, the relationship between the rank of the Cartesian product code C1 × C 2 × × Cs over Z r1 × Z r2 × × Zrsand C1 , C 2,
LIU Xiu-sheng
doaj   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Are the MDS-UPDRS-based composite scores clinically applicable?

open access: yes, 2018
BACKGROUND: The International Parkinson and Movement Disorder Society-sponsored UPDRS (MDS-UPDRS) is a powerful clinical outcome measure. OBJECTIVES: To evaluate the feasibility of various MDS-UPDRS-based composite scores and determine their minimal ...
Janszky, József Vladimír   +13 more
core   +1 more source

An evaluation of machine learning and latent semantic analysis in text sentiment classification

open access: yesTechnical Transactions, 2020
In this paper, we compare the following machine learning methods as classifiers for sentiment analysis: k – nearest neighbours (kNN), artificial neural network (ANN), support vector machine (SVM), random forest.
Miazga Justyna, Hachaj Tomasz
doaj   +1 more source

On negacyclic MDS-convolutional codes

open access: yesLinear Algebra and its Applications, 2014
New families of classical and quantum optimal negacyclic convolutional codes are constructed in this paper. This optimality is in the sense that they attain the classical (quantum) generalized Singleton bound. The constructions presented in this paper are performed algebraically and not by computational search.
openaire   +3 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

International Building Code: 2009 [PDF]

open access: yes, 2009
Manual describing best practices for constructing buildings that meet safety and energy requirements; appropriate building materials and use; and related issues: "This comprehensive building code establishes minimum regulations for building systems using
International Code Council
core  

Myelodysplastic syndromes: Aspects of current medical care and economic considerations in Germany [PDF]

open access: yes, 2008
Myelodysplastic syndromes (MDS) are a heterogeneous group of diseases mainly affecting older people. The use of an increasing number of therapeutic options depends on a systematic risk stratification of the patients.
Gattermann, Norbert   +19 more
core   +1 more source

MDS Generalized Convertible Code [PDF]

open access: yes
In this paper, we consider the convertible codes with the maximum distance separable (MDS) property, which can adjust the code rate according to the failure rates of devices.
Tang, Xiaohu, Cai, Han, Ge, Songping
core   +1 more source

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