Results 91 to 100 of about 2,782,523 (317)

Navigating a newly diagnosed cancer through clinician-facilitated discussions of health-related patient values: a qualitative analysis

open access: yesBMC Palliative Care, 2022
Background Advance care planning, the process through which patient values and goals are explored and documented, is a core quality indicator in cancer care. However, patient values are predominantly elicited at the end of life; patient values earlier in
Kathleen A. Lynch   +10 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

An evaluation of machine learning and latent semantic analysis in text sentiment classification

open access: yesTechnical Transactions, 2020
In this paper, we compare the following machine learning methods as classifiers for sentiment analysis: k – nearest neighbours (kNN), artificial neural network (ANN), support vector machine (SVM), random forest.
Miazga Justyna, Hachaj Tomasz
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

MDR codes and self-dual codes on Cartesian product codes

open access: yesTongxin xuebao, 2010
A Cartesian product code of the linear codes C1 , , C s in 1 , ,Z r Z rs was defined. According to the theorem of submodulo isomorphism, the relationship between the rank of the Cartesian product code C1 × C 2 × × Cs over Z r1 × Z r2 × × Zrsand C1 , C 2,
LIU Xiu-sheng
doaj   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

X-code: MDS array codes with optimal encoding [PDF]

open access: yes, 1999
We present a new class of MDS (maximum distance separable) array codes of size n×n (n a prime number) called X-code. The X-codes are of minimum column distance 3, namely, they can correct either one column error or two column erasures. The key novelty in
Bruck, Jehoshua, Xu, Lihao
core   +1 more source

On negacyclic MDS-convolutional codes

open access: yesLinear Algebra and its Applications, 2014
New families of classical and quantum optimal negacyclic convolutional codes are constructed in this paper. This optimality is in the sense that they attain the classical (quantum) generalized Singleton bound. The constructions presented in this paper are performed algebraically and not by computational search.
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Repeated-Root Constacyclic Codes Over the Chain Ring Fpm[u]/⟨u3

open access: yesIEEE Access, 2020
Let Z = Fpm[u]/(u3) be the finite commutative chain ring, where p is a prime, m is a positive integer and Fpm is the finite field with pm elements. In this paper, we determine all repeated-root constacyclic codes of arbitrary lengths over Z and their ...
Tania Sidana, Anuradha Sharma
doaj   +1 more source

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