Results 71 to 80 of about 35,611 (258)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Direct Construction of Optimal Rotational-XOR Diffusion Primitives
IACR Transactions on Symmetric Cryptology, 2017 As a core component of SPN block cipher and hash function, diffusion layer is mainly introduced by matrices built from maximum distance separable (MDS) codes.
Zhiyuan Guo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
On Group Codes Over Elementary Abelian Groups
Sultan Qaboos University Journal for Science, 2003 For group codes over elementary Abelian groups we present definitions of the generator and the parity check matrices, which are matrices over the ring of endomorphism of the group.
Adnan A. Zain
doaj +1 more source
Cyclic Low-Density MDS Array Codes [PDF]
, 2006 We construct two infinite families of low density MDS array codes which are also cyclic. One of these families includes the first such sub-family with redundancy parameter r > 2.
Jehoshua Bruck +3 more
core +2 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
, 2003 We present families of quantum error-correcting codes which are optimal in the sense that the minimum distance is maximal. These maximum distance separable (MDS) codes are defined over q-dimensional quantum systems, where q is an arbitrary prime power ...
MacWilliams F. J. +3 more
core +1 more source
On negacyclic MDS-convolutional codes
Linear Algebra and its Applications, 2014 New families of classical and quantum optimal negacyclic convolutional codes are constructed in this paper. This optimality is in the sense that they attain the classical (quantum) generalized Singleton bound. The constructions presented in this paper are performed algebraically and not by computational search.
openaire +2 more sources