Results 121 to 130 of about 37,729 (256)

Extracting effective solutions hidden in large language models via generated comprehensive specialists: case studies in developing electronic devices

Communications Materials
Recently, the use of large-scale language models (LLMs) for generating research ideas and constructing scientific hypotheses has been gaining significant attention.
Hikari Tomita, Nobuhiro Nakamura, Shoichi Ishida, Toshio Kamiya, Kei Terayama   +4 more
doaj   +1 more source

Reduced Muscle Force in Dystrophic DMDΔ52 Pigs Is Incompletely Restored by Systemic Transcript Reframing (DMDΔ51–52)

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease caused by mutations in the DMD gene, leading to dystrophin deficiency and progressive degeneration of skeletal and cardiac muscles. Pigs lacking DMD exon 52 (DMDΔ52) are a clinically severe model for DMD, mimicking molecular, functional and pathological hallmarks of the ...
Michaela Blasi, Hristiyan Hristov, Jan B. Stöckl, Martin Kraetzl, Sonja Fiedler, Elisabeth Kemter, Mayuko Kurome, Barbara Kessler, Josep M. Cambra, Valeri Zakhartchenko, Maggie C. Walter, Christian Kupatt, Nikolai Klymiuk, Thomas Fröhlich, Andreas Blutke, Michael Stirm, Florian Jaudas, Eckhard Wolf   +17 more
wiley   +1 more source

Trees and asymptotic developments for fractional stochastic differential equations [PDF]

, 2006
In this paper we consider a n-dimensional stochastic differential equation driven by a fractional Brownian motion with Hurst parameter H>1/3. After solving this equation in a rather elementary way, following the approach of Gubinelli, we show how to ...
Neuenkirch, Andreas, Nourdin, Ivan, Rößler, Andreas, Tindel, Samy   +3 more
core   +4 more sources

Digital efforts in Spanish for enrolling Latino adults in the Brain Health Registry

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 4, October-December 2025.
Abstract INTRODUCTION Previous culturally informed digital inclusion efforts in English effectively enrolled Latino adults into the Brain Health Registry (BHR), an online Alzheimer's disease (AD)–related registry. Because these efforts were in English only, we did not successfully reach individuals from the U.S.
Miriam T. Ashford, Anna Aaronson, Chengshi Jin, Monica R. Camacho, Joseph Eichenbaum, Aaron Ulbricht, Roxanne Alaniz, Jennefer Sorce, Sandhya Kannan, Lourdes Guerrero, David X. Marquez, Derek Flenniken, Juliet Fockler, Diana Truran, R. Scott Mackin, Monica Rivera Mindt, Alejandra Morlett Paredes, Hector M. González, Michael W. Weiner, Rachel L. Nosheny   +19 more
wiley   +1 more source

Genomic biomarkers in prostate cancer. [PDF]

, 2018
Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer.
Cooperberg, Matthew R, Feng, Felix Y, Kornberg, Zachary, Spratt, Daniel E   +3 more
core  

Dystrophin isoform deficiency and upper‐limb and respiratory function in Duchenne muscular dystrophy

Developmental Medicine &Child Neurology, Volume 67, Issue 10, Page 1280-1289, October 2025.
Mary Chesshyre, Deborah Ridout, Georgia Stimpson, Valeria Ricotti, Silvana De Lucia, Erik H Niks, Volker Straub, Laurent Servais, Jean‐Yves Hogrel, Giovanni Baranello, Adnan Manzur, UK NorthStar Clinical Network and Francesco Muntoni* on behalf of the iMDEX network.
Mary Chesshyre, Deborah Ridout, Georgia Stimpson, Valeria Ricotti, Silvana De Lucia, Erik H. Niks, Volker Straub, Laurent Servais, Jean‐Yves Hogrel, Giovanni Baranello, Adnan Manzur, UK NorthStar Clinical Network, Francesco Muntoni, on behalf of the iMDEX Network, Joana Domingos, Victoria Selby, Amy Wolfe, Lianne Abbott, Efthymia Panagiotopoulou, Mario Iodice, Maria Ash, Imelda de Groot, Merel Jansen, Maaike Pelsma, Marian Bobbert, Menno Van Der Holst, Yvonne D. Krom, Marjolein J. van Heur‐Neuman, Thomas Voit, Valérie Decostre, Stéphanie Gilabert, Michela Guglieri, Alexander Murphy, Anna Mayhew, Mariacristina Scoto, Anna Sarkozy, Pinki Munot, Stephanie Robb, Elaine Chan, V Robinson, W Girshab, V Crook, E Milev, L Abbott, A Wolfe, E O’Reilly, J Watts‐When, N Burnett, R Thomas, R Terespolsky, O Martinaeu, J Longatto, C Bettolo, M Guglieri, J Diaz‐Manera, G Tasca, M Elseed, R Muni‐Lofra, M James, D Moat, J Sodhi, K Wong, E Robinson, E Groves, R Rabb, H McMurchie, H Chase, Tracey Willis, C Rylance, N Birchall, E Wright, A Childs, K Pysden, C Martos, D Roberts, L. Pallant, S Walker, A Henderson, R Madhu, R Karuvattil, Y Balla, S Gregson, S Clark, E Wraige, H Jungbluth, V Gowda, M Vanegas, J. Sheehan, A Schofield, C Smith, I Hughes, E Whitehouse, S Warner, E Reading, N Emery, J Moustoukas, K Strachan, M Ong, M Atherton, N Mills, S Sanchez Marco, A Saxena, K Skone, J TeWaterNaude, H Davis, C Wood, A Majumdar, A Murugan, I Guarino, R Tomlinson, H Jarvis, L Wills, C Frimpong, J Watson, G Cobb, G Robertson, P Brink, J Burslem, C Adams, J Wong, S Joseph, I Horrocks, J Dunne, M DiMarco, S Brown, S McKenzie, K Torne, R Mohamed, V Velmurugan, M Prasad, S Sedehizadeh, A Schugal, R Keetley, S Williamson, K Payne, E Dowling, P Fenty, C de Goede, A Parkes, K Baxter, M Illingworth, N Bhangu, S Geary, J Palmer, K Shill, S Tirupathi, A Shah, D O’Donogue, J McVeigh, J McFetridge, G Nicfhirleinn, H Beattie, T Leyland, K Stevenson, N Hussain, D Baskaran, Z Lambat, R Sullivan, L Locke, G Ambegaonkar, D Krishnakumar, J Taylor, J Moores, E Stephen, J Tewnion, S Ramdas, M Sa, A Skippen, M Khries, C Lilien, H Ramjattan, F Taylor, H English, K Stewart, F Flint, E Bartram, R Noble   +176 more
wiley   +1 more source

Molecular and genetic mapping of the mouse mdx locus

Genomics, 1988
mdx is an X-linked muscular dystrophy mutant of the mouse and a putative homolog of the human X-linked muscular dystrophy locus--Duchenne muscular dystrophy (DMD). Utilizing a C57BL/10/Mus Spretus interspecific cross in which the mdx mutation was segregating, we have constructed a detailed genetic map around the mdx locus on the mouse X chromosome.
Stephen D.M. Brown, Neil Brockdorff, J.E. Morgan, S.M. Forrest, G. R. Coulton, J. S. Cavanna, Kay E. Davies   +6 more
openaire   +2 more sources

The Landscape of SPP1 + Macrophages Across Tissues and Diseases: A Comprehensive Review

Immunology, Volume 176, Issue 2, Page 179-196, October 2025.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source

A homologue of dystrophin is expressed at the neuromuscular junctions of normal individuals and DMD patients, and of normal and mdx mice Immunological evidence [PDF]

, 1991
F. Pons, N Augier, Jocelyne Léger, Aude Robert, F.M.S. Tomé, Michel Fardeau, Thomas Voit, L. V. B. Nicholson, Dominique Mornet, J. Léger   +9 more
openalex   +1 more source

Effect of Sildenafil on mdx Skeletal Muscle

The FASEB Journal, 2008
Duchenne muscular dystrophy (DMD) affects 1 in 3,500 boys and is a severe X‐linked disease caused by a complete loss of dystrophin. DMD patients are born healthy but by age five, develop progressive skeletal muscle necrosis, fibrosis and abnormal hypertrophy.
Joseph A. Beavo, Justin M. Percival, Stanley C. Froehner, Heidi Gray, Candace M Parchen   +4 more
openaire   +2 more sources