Results 111 to 120 of about 23,197,056 (323)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
What Does ‘Experiencing Meaning’ Mean?
, 2017 Wittgenstein links the strange phenomenon of experiencing meaning to the more familiar phenomenon of seeing-as, or noticing an aspect. His interest in the subject seems to have been sparked by the work of William James, and this chapter examines both what he has to say on the matter (some of which long pre-dates the 'third' Wittgenstein stage) and its ...
openaire +2 more sources
The Annals of Statistics, 1974 General theorems on asymptotic normality of randomly trimmed and Winsorized means are obtained. A new small sample studentization is proposed. Many examples are presented. The two sample problem is also considered.
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
APPLICATION OF DESCRIPTIVE STATISTICS METHODS IN CUSTOMS RISK ANALYSIS
Финансы: теория и практика, 2017 Improving of risk management’s tools is one of the important ways of increasing the efficiency of customs control. A development of statistical methods to identify potential customs risks is the most promising area of research in this context.
O. E. Kudryavtsev, S. E. Tamrazyan
doaj
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Mean curvature flow without singularities
, 2012 We study graphical mean curvature flow of complete solutions defined on subsets of Euclidean space. We obtain smooth long time existence. The projections of the evolving graphs also solve mean curvature flow.
Schnürer, Oliver C. +1 more
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source