Results 61 to 70 of about 531,242 (294)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

COMPARISON OF MISSING VALUE IMPUTATION USING MEAN, BAYESIAN KNN, AND NON-BAYESIAN KNN ON TEP GENE EXPRESSION DATA

open access: yesMedia Statistika
Analysis of gene expression data, particularly in cancer data, often faces challenges due to the presence of missing values. One approach to overcome this is data imputation.
Mastika Mastika   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Modeling Critical Flow through Choke for a Gas-condensate Reservoir Based on Drill Stem Test Data [PDF]

open access: yesIranian Journal of Oil & Gas Science and Technology, 2017
Gas-condensate reservoirs contain hydrocarbon fluids with characteristics between oil and gas reservoirs and a high gas-liquid ratio. Due to the large gas-liquid ratio, wellhead choke calculations using the empirical equations such as Gilbert may contain
Ahmad Lak   +3 more
doaj   +1 more source

The mean absolute error of germination rate for the three rice varieties. [PDF]

open access: yes, 2023
The mean absolute error of germination rate for the three rice varieties.
Binbin Xiong (14322196)   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Minimum Mean Absolute Error Predictors for Lossless Image Coding

open access: yesIEICE Transactions on Information and Systems, 2008
In this paper, we investigate minimum mean absolute error (mmae) predictors for lossless image coding. In some prediction-based lossless image coding systems, coding performance depends largely on the efficiency of predictors. In this case, minimum mean square error (mmse) predictors are often used.
Yoshihiko Hashidume   +2 more
openaire   +2 more sources

Mean Absolute Error (MAE) of computed coral polyp activity per image. [PDF]

open access: yes, 2023
Mean Absolute Error (MAE) of computed coral polyp activity per image.
Pål Buhl-Mortensen (472439)   +4 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy