Results 71 to 80 of about 1,404,374 (329)

Convergence of online $k$-means

open access: yes, 2022
We prove asymptotic convergence for a general class of $k$-means algorithms performed over streaming data from a distribution: the centers asymptotically converge to the set of stationary points of the $k$-means cost function. To do so, we show that online $k$-means over a distribution can be interpreted as stochastic gradient descent with a stochastic
Dasgupta, Sanjoy   +2 more
openaire   +2 more sources

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

The Convergence of Double-Indexed Weighted Sums of Martingale Differences and Its Application

open access: yesAbstract and Applied Analysis, 2014
We investigate the complete moment convergence of double-indexed weighted sums of martingale differences. Then it is easy to obtain the Marcinkiewicz-Zygmund-type strong law of large numbers of double-indexed weighted sums of martingale differences ...
Wenzhi Yang   +3 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Convergence Analysis for the SMC-MeMBer and SMC-CBMeMBer Filters

open access: yesJournal of Applied Mathematics, 2012
The convergence for the sequential Monte Carlo (SMC) implementations of the multitarget multi-Bernoulli (MeMBer) filter and cardinality-balanced MeMBer (CBMeMBer) filters is studied here.
Feng Lian   +3 more
doaj   +1 more source

On convergence fields of Nörlund means [PDF]

open access: yesProceedings of the American Mathematical Society, 1956
If 0n = s+o(l) when nw, the sequence { s, } (of complex numbers) is said to be limitable N(p) to the value s. If 0n =o(1), we shall write snGo(N(p)), denoting by o(N(p)) the set of all the sequences limitable N(p) to zero. If o-n=a(l) when ncc',2 the sequence {s4I is said to be absolutely limitable N(p), and we shall write snCa(N(p)), denoting by a(N(p)
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Some Spaces of Double Sequences Obtained through Invariant Mean and Related Concepts

open access: yesAbstract and Applied Analysis, 2013
We introduce some double sequences spaces involving the notions of invariant mean (or -mean) and -convergence for double sequences while the idea of -convergence for double sequences was introduced by Çakan et al.
S. A. Mohiuddine, Abdullah Alotaibi
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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