Results 151 to 160 of about 5,121,571 (362)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Brain asymmetry is globally different in males and females: exploring cortical volume, area, thickness, and mean curvature. [PDF]

Cereb Cortex, 2023
Dumitru ML.
europepmc   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

Detection of Corneal Ectasia Using OCT Maps of Pachymetry and Posterior Surface Mean Curvature. [PDF]

J Refract Surg, 2022
Pavlatos E, Chen S, Chamberlain W, Huang D, Li Y.   +4 more
europepmc   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Local Well-Posedness of Skew Mean Curvature Flow for Small Data in d ≥ 4 Dimensions. [PDF]

Commun Math Phys, 2022
Huang J, Tataru D.
europepmc   +1 more source

The role of the mean curvature in the immersion theory of surfaces [PDF]

, 1940
Howard W. Alexander
openalex   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Improved Detection of Chronic Obstructive Pulmonary Disease at Chest CT Using the Mean Curvature of Isophotes. [PDF]

Radiol Artif Intell, 2022
Savadjiev P, Gallix B, Rezanejad M, Bhatnagar S, Semionov A, Siddiqi K, Forghani R, Reinhold C, Eidelman DH, Dandurand RJ.   +9 more
europepmc   +1 more source

On stable hypersurfaces with constant mean curvature in Euclidean spaces [PDF]

arXiv, 2012
In this paper, we derive curvature estimates for strongly stable hypersurfaces with constant mean curvature immersed in $\mathbb{R}^{n+1}$, which show that the locally controlled volume growth yields a globally controlled volume growth if $\partial M=\emptyset$.
arxiv