Results 51 to 60 of about 5,469,641 (325)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

On approximations of the curve shortening flow and of the mean curvature flow based on the DeTurck trick [PDF]

open access: yes, 2016
In this paper we discuss novel numerical schemes for the computation of the curve shortening and mean curvature flows that are based on special reparametrizations.
C. M. Elliott, Hans Fritz
semanticscholar   +1 more source

Existence and uniqueness for anisotropic and crystalline mean curvature flows [PDF]

open access: yesJournal of The American Mathematical Society, 2017
An existence and uniqueness result, up to fattening, for crystalline mean curvature flows with forcing and arbitrary (convex) mobilities, is proven. This is achieved by introducing a new notion of solution to the corresponding level set formulation. Such
A. Chambolle   +3 more
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Mean Curvature in the Light of Scalar Curvature [PDF]

open access: yes, 2018
We formulate several conjectures on mean convex domains in the Euclidean spaces, as well as in more general spaces with lower bonds on their scalar curvatures, and prove a few theorems motivating these conjectures.
M. Gromov
semanticscholar   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Graphs with constant mean curvature in the 3-hyperbolic space

open access: yesAnais da Academia Brasileira de Ciências, 2002
In this work we will deal with disc type surfaces of constant mean curvature in the three dimensional hyperbolic space which are given as graphs of smooth functions over planar domains.
PEDRO A. HINOJOSA
doaj   +1 more source

Two new preconditioners for mean curvature-based image deblurring problem

open access: yesAIMS Mathematics, 2021
The mean curvature-based image deblurring model is widely used to enhance the quality of the deblurred images. However, the discretization of the associated Euler-Lagrange equations produce a nonlinear ill-conditioned system which affect the convergence ...
Shahbaz Ahmad   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy