Results 51 to 60 of about 255,201 (317)

A local regularity theorem for mean curvature flow with triple edges

open access: yes, 2017
Mean curvature flow of clusters of n-dimensional surfaces in R^{n+k} that meet in triples at equal angles along smooth edges and higher order junctions on lower dimensional faces is a natural extension of classical mean curvature flow.
Schulze, Felix, White, Brian
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Convergence rate of the weighted conformal mean curvature flow

open access: yesAnalysis and Geometry in Metric Spaces
In this article, we study the convergence rate of the following Yamabe-type flow Rϕ(t)m=0inMand∂∂tg(t)=2(hϕ(t)m−Hϕ(t)m)g(t)∂∂tϕ(t)=m(Hϕ(t)m−hϕ(t)m)on∂M{R}_{\phi \left(t)}^{m}=0\hspace{0.33em}\hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}M\hspace ...
Hamanaka Shota, Tung Ho Pak
doaj   +1 more source

Combined Effects of Flow Diverting Strategies and Parent Artery Curvature on Aneurysmal Hemodynamics: A CFD Study.

open access: yesPLoS ONE, 2015
PurposeFlow diverters (FD) are increasingly being considered for treating large or giant wide-neck aneurysms. Clinical outcome is highly variable and depends on the type of aneurysm, the flow diverting device and treatment strategies.
Jinyu Xu   +7 more
doaj   +1 more source

Noncollapsing in mean-convex mean curvature flow [PDF]

open access: yesGeometry & Topology, 2012
We provide a direct proof of a non-collapsing estimate for compact hypersurfaces with positive mean curvature moving under the mean curvature flow: Precisely, if every point on the initial hypersurface admits an interior sphere with radius inversely proportional to the mean curvature at that point, then this remains true for all positive times in the ...
openaire   +4 more sources

Uniformly Compressing Mean Curvature Flow [PDF]

open access: yesThe Journal of Geometric Analysis, 2018
Michor and Mumford showed that the mean curvature flow is a gradient flow on a Riemannian structure with a degenerate geodesic distance. It is also known to destroy the uniform density of gridpoints on the evolving surfaces. We introduce a related geometric flow which is free of these drawbacks.
Wenhui Shi, Dmitry Vorotnikov
openaire   +3 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Diffuse-interface approximation and weak–strong uniqueness of anisotropic mean curvature flow

open access: yesEuropean Journal of Applied Mathematics
The purpose of this paper is to derive anisotropic mean curvature flow as the limit of the anisotropic Allen–Cahn equation. We rely on distributional solution concepts for both the diffuse and sharp interface models and prove convergence using relative ...
Tim Laux   +2 more
doaj   +1 more source

Evolution of the first eigenvalue of the Laplace operator and the p-Laplace operator under a forced mean curvature flow

open access: yesOpen Mathematics, 2020
In this paper, we discuss the monotonicity of the first nonzero eigenvalue of the Laplace operator and the p-Laplace operator under a forced mean curvature flow (MCF).
Qi Xuesen, Liu Ximin
doaj   +1 more source

APPROXIMATION OF THE ANISOTROPIC MEAN CURVATURE FLOW [PDF]

open access: yesMathematical Models and Methods in Applied Sciences, 2007
In this paper, we provide simple proofs of consistency for two well-known algorithms for mean curvature motion, Almgren–Taylor–Wang's1 variational approach, and Merriman–Bence–Osher's algorithm.29 Our techniques, based on the same notion of strict sub- and superflows, also work in the (smooth) anisotropic case.
CHAMBOLLE A, NOVAGA, MATTEO
openaire   +2 more sources

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