Results 61 to 70 of about 266,343 (229)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Dynamics of convex mean curvature flow
Journal für die reine und angewandte Mathematik (Crelles Journal)Abstract There is an extensive and growing body of work analyzing convex ancient solutions to mean curvature flow (MCF), or equivalently of rescaled mean curvature flow (RMCF). The goal of this paper is to complement the existing literature, which analyzes ancient solutions one at a time, by considering the space 𝑋 of all convex ...
Sigurd Angenent +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Mean curvature blow up in mean curvature flow
, 2009 In this note we establish that finite-time singularities of the mean curvature flow of compact Riemannian submanifolds are characterised by the blow up of the mean curvature.
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Noncollapsing in mean-convex mean curvature flow [PDF]
Geometry & Topology, 2012 We provide a direct proof of a non-collapsing estimate for compact hypersurfaces with positive mean curvature moving under the mean curvature flow: Precisely, if every point on the initial hypersurface admits an interior sphere with radius inversely proportional to the mean curvature at that point, then this remains true for all positive times in the ...
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FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Local Well-Posedness of Skew Mean Curvature Flow for Small Data in d ≥ 4 Dimensions. [PDF]
Commun Math Phys, 2022 Huang J, Tataru D.
europepmc +1 more source
The mean curvature at the first singular time of the mean curvature flow
Annales de l'Institut Henri Poincaré C, Analyse non linéaire, 2010 Consider a family of smooth immersions F( \cdot ,t):M^{n}\rightarrow \mathbb{R}^{n + 1} of closed hypersurfaces in \mathbb{R}^{n + 1} moving by the mean curvature flow \frac{\partial F(p,t)}{\partial t} = −
Le, Nam Q., Sesum, Natasa
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