Results 81 to 90 of about 6,607,246 (296)

Comparison of lingual mucosa and buccal mucosa grafts used in inlay urethroplasty in failed hypospadias of pre-pubertal boys in a Chinese group. [PDF]

PLoS ONE, 2017
The purpose of this study was to compare the outcomes of the buccal mucosa and lingual mucosa used in children who received multiple failed hypospadias surgeries.We conducted a retrospective study of 62 children who received buccal or lingual mucosa ...
Jin Hongyong, Chen Shuzhu, Wu Min, Ye Weijing, Liu Yidong   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Nonexistence of mean curvature flow solitons with polynomial volume growth immersed in certain semi-Riemannian warped products

Advances in Nonlinear Analysis
Our purpose is to establish nonexistence results concerning complete noncompact mean curvature flow solitons with polynomial volume growth immersed in certain semi-Riemannian warped products, under mild constraints on the warping and soliton functions ...
Batista Márcio, Molica Bisci Giovanni, de Lima Henrique F., Gomes Wallace F.   +3 more
doaj   +1 more source

Modelling Free Flow Speed on Two-Lane Rural Highways in Bosnia and Herzegovina

Promet (Zagreb), 2014
Free flow speed is used as a parameter in transportation planning and capacity analysis models, as well as speed-flow diagrams. Many of these models suggest estimating free flow speed according to measurements from similar highways, which is not a ...
Ivan Lovrić, Dražen Cvitanić, Deana Breški   +2 more
doaj   +1 more source

Singular perturbations of mean curvature flow

Journal of Differential Geometry, 2007
We introduce a regularization method for mean curvature flow of a submanifold of arbitrary codimension in the Euclidean space, through higher order equations. We prove that the regularized problems converge to the mean curvature flow for all times before the first singularity.
GIOVANNI BELLETTINI, MANTEGAZZA, Carlo Maria, MATTEO NOVAGA   +2 more
openaire   +9 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Flow along a long thin cylinder [PDF]

, 2008
Two different approaches have been used to calculate turblent flow along a long thin culinder where the flow is aligned with the cylinder. A boundary-layer code is used to predict the mean flow for very long cylinders (length to ratio of up to O(106 ...
O. R. TUTTY, Tutty, O.R.
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Uniform Gaussian Bounds for Subelliptic Heat Kernels and an Application to the Total Variation Flow of Graphs over Carnot Groups

Analysis and Geometry in Metric Spaces, 2013
In this paper we study heat kernels associated with a Carnot group G, endowed with a family of collapsing left-invariant Riemannian metrics σε which converge in the Gromov- Hausdorff sense to a sub-Riemannian structure on G as ε→ 0.
Capogna Luca, Citti Giovanna, Manfredini Maria   +2 more
doaj   +1 more source