Results 161 to 170 of about 72,082 (280)

Portfolio Decisions with Higher Order Moments [PDF]

open access: yes
In this paper, we address the global optimization of two interesting nonconvex problems in finance. We relax the normality assumption underlying the classical Markowitz mean-variance portfolio optimization model and consider the incorporation of skewness
Berc Rustem, P. M. Kleniati
core  

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall   +3 more
wiley   +1 more source

Spike detection in the wild: Screening of suspected temporal lobe epilepsy cases using a tailored 2‐channel wearable EEG

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges   +4 more
wiley   +1 more source

An algorithm for seizure detection in rodents

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky   +9 more
wiley   +1 more source

Robust and diverse multidimensional statistical moments in dual-band entomological lidar for improved real-time insect monitoring. [PDF]

open access: yesJ Exp Biol
Dreyer D   +12 more
europepmc   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

Early cerebral palsy risk screening through wearable accelerometry in infants under nine weeks. [PDF]

open access: yesSci Rep
Alvarado J   +8 more
europepmc   +1 more source

Decentralized Federated Learning for Wind Turbine Bearing Prognostics Under Data Scarcity and Statistical Heterogeneity

open access: yesEnergy Science &Engineering, EarlyView.
This paper proposes a decentralized peer‐to‐peer federated learning framework for wind turbine bearing remaining useful life prediction, introducing a virtual client paradigm in which statistical health indicators serve as independent feature‐level clients—enabling privacy‐preserving collaborative prognostics from a single physical asset under ...
Jihene Sidhom   +2 more
wiley   +1 more source

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