Results 61 to 70 of about 249,030 (262)

Factorial design to quantify the influence of extrusion parameters in the mean residence time

Polímeros, 2010
Residence time distribution (RTD) is a very important parameter in extrusion, either for simple polymer processing or for special processes like compounding, blending, reactive compatibilization, and controlled degradation.
Tomás J. A. de Mélo, Luís A Pinheiro, Sebastião V Canevarolo   +2 more
doaj  

Material Residence Time in Marine Canopies Under Wave-Driven Flows

Frontiers in Marine Science, 2020
Coastal canopies (e.g., seagrasses, coral reefs, and kelp forests) are vitally important ecosystems that provide a range of ecological services (e.g., oxygen production, sediment stabilization and trapping, and recycling of nutrients).
Maryam Abdolahpour, Maryam Abdolahpour, Marco Ghisalberti, Kathryn McMahon, Paul Lavery   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Tracing groundwater recharge conditions based on environmental isotopes and noble gases, Lom depression, Bulgaria

Journal of Hydrology: Regional Studies, 2019
Study region: Lom depression, Bulgaria. Study focus: A multi-tracer investigation was applied to identify the recharge conditions and isotope hydrological character of four aquifers in the Lom depression (Northwest Bulgaria) using environmental isotopes (
Marianna Túri, Mihály Molnár, Tatiana Orehova, Aglaida Toteva, Vladimir Hristov, Aleksey Benderev, Anikó Horváth, László Palcsu   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Assessment of runoff composition and residence time using stable isotopes and hydrochemical characteristics in Urumqi River Basin, northwest China

Journal of Hydrology: Regional Studies
Study region: The Urumqi River, nourished by glaciers in arid regions of northwest China, plays a crucial role in the economic, ecological, and social development of the region.
Siqi Wu, Fang Feng, Shuang Jin, Zhongqin Li, Michael A. Urban, Qiaohua Huang, Qiannian Shi   +6 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

mean residence time

, 2014
Citation: 'mean residence time' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03785 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Biochar as a Platform to Increase Manure Carbon Residence Time in Soil

GCB Bioenergy
Manure and biochar (BC) based practices influence soil carbon (C) dynamics. However, manure does not enhance soil carbon (C) as quickly as BC does. Data on BC from different feedstocks and their co‐application with manure in stabilizing labile manure C ...
Chumki Banik, Poonam Sashidhar, Ryan G. Smith, Santanu Bakshi   +3 more
doaj   +1 more source