Results 251 to 260 of about 17,553,550 (282)

Comments on mean residence time determination

Journal of Pharmacokinetics and Pharmacodynamics, 1985
In a recent paper, D. O. Chanter challenged the applicability of the use of statistical moments in estimating mean residence time and proposed an alternative approach. Errors in that paper are pointed out which involve the improper equating of whole-body amount of drug with plasma amount of drug in a kinetic system.
E M, Landaw, D, Katz
exaly   +3 more sources

Sampling strategies for noncompartmental estimation of mean residence time

Journal of Pharmacokinetics and Biopharmaceutics, 1983
An optimization procedure is presented for selecting sample times for estimating mean residence time using noncompartmental data analysis. Performance of this experimental design strategy is evaluated using Monte Carlo simulations of a model for digoxin kinetics.
D Z, D'Argenio, D, Katz
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Residence Times and Mean Concentrations

1985
The residence time T of a single particle is the time spent in the atmosphere of that particle. From the definitions in section 3 it follows that $$ E(c(t))\, = \,\int\limits_{ - \infty }^t {E(e^{ - (\Lambda (t) - \Lambda (s))} dq(s))} . $$
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Dosage Intervals Based on Mean Residence times

Journal of Pharmaceutical Sciences, 1987
It is shown that a suitable dosage interval, tau, can be estimated by a factor times the sum of the mean residence time (MRT) of the central compartment (MRTC) and the MRT of the absorption site (MRTA). This value of tau will provide a ratio, maximum steady-state plasma concentration: minimum steady-state plasma concentration, which averages ...
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Mean residence time by hierarchical clustering analysis

Theoretical Chemistry Accounts, 2016
A revised method, based on the hierarchical clustering data analysis technique, is proposed as an improved approach to estimate the mean residence time (MRT) related to the interaction between a molecule and its solvent as described via molecular dynamics simulations.
L. Guzzardi, D. F. Cazar, C. V. del Hierro, F. J. Torres, M. A. Méndez   +4 more
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Mean Residence Time of a Liquid in a Trickling Filter

Journal of the Sanitary Engineering Division, 1959
Pilot plant research studies aimed at broadening the basic knowledge relative to the performance of trickling filters were initiated. This paper presents the results of initial hydraulic studies in which the mean residence time was determined for tap water applied to columns packed with spherical media under conditions of varying hydraulic loading ...
Morton D. Sinkoff, Ralph Porges, James H. McDermott   +2 more
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A method for calculating the mean residence times of catenary metabolites

Biopharmaceutics & Drug Disposition, 1991
AbstractA method for calculating the mean residence times of metabolites in the body, systemic circulation, and peripheral tissue is described. The calculations require the AUC, AUMC, and derivatives of the plasma concentration versus time curves of the metabolite and its precursor.
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Mean Residence Time and Residence Time Distribution When Sawdust Is Dried in Continuous Dryers

Drying Technology, 2008
Information on the mean residence time and the residence time distribution is of importance when optimizing a continuous dryer. In this study, an industrial method for determining the mean residence time is developed. The produced method is benchmarked on a laboratory scale against the stop-and-empty method.
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A derivation of mean residence time.

European journal of drug metabolism and pharmacokinetics, 1992
MRT was derived as the mean value of the continuously distributed random variable residence time. Provide that elimination kinetics is linear and that elimination takes place exclusively from the central compartment, MRT can be calculated from the ratio AUMC/AUC.
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Derivation of Mean Cell Residence Time Formula

Journal of Environmental Engineering, 1998
Mean cell residence time or MCRT has emerged as the leading design and operation parameter for suspended growth wastewater treatment processes. The commonly used MCRT formula has never been shown to represent the time the microorganisms spend in the system.
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