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Mean residence time in organs in toxicokinetic studies

Mean residence time in organs in toxicokinetic studies
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Mean residence time in the body versus mean residence time in the central compartment

Journal of Pharmacokinetics and Biopharmaceutics, 1985
Mean residence time in the body may be determined by noncompartmental methods following any type of input process into the sampled compartment. Mean residence time in the central compartment can be determined following an intravenous bolus dose, as it requires calculation of the concentration at zero time. For any other input process the mean residence
Leslie Z Benet, Benet Leslie Z
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Mean residence time in peripheral tissue

Journal of Pharmacokinetics and Biopharmaceutics, 1987
The published methods for determining the mean residence time for drugs in peripheral tissue are reviewed in terms of assumptions involved, advantages and disadvantages. A method for determining mean transit time in peripheral tissue is proposed; this may be a more useful indicator of the tissue retention properties for drug compounds.
P J, McNamara, J C, Fleishaker, T L, Hayden   +2 more
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Mean residence time for drugs subject to enterohepatic cycling

Journal of Pharmacokinetics and Biopharmaceutics, 1989
A physiologically realistic model of enterohepatic cycling (EHC) which includes separate liver and gallbladder compartments, discontinuous gallbladder emptying and first-order absorption from both an oral formulation and secreted bile (kapo and kab, respectively) has been developed.
Shepard, Theresa A., Lockwood, Graham F., Aarons, Leon J.; id_orcid 0000-0003-2704-6570, Abrahams, I. David   +3 more
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Mean Residence Time and Residence Time Distribution When Sawdust Is Dried in Continuous Dryers

Drying Technology, 2008
Information on the mean residence time and the residence time distribution is of importance when optimizing a continuous dryer. In this study, an industrial method for determining the mean residence time is developed. The produced method is benchmarked on a laboratory scale against the stop-and-empty method.
Roger Renström
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Danckwerts’ law for mean residence time revisited

Chemical Engineering Science, 2006
This paper shows that Danckwerts’ law for mean residence time in a vessel with continuous and steady through∞ow holds for a stochastic model based on a Markov chain for the particle spatial position, under a set of three very general conditions on the transfer probabilities.
Timo Gottschalk, Herold G. Dehling, Alex C. Hoffmann   +2 more
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Mean residence time of lagoons in shallow vegetated floodplains

Hydrological Processes, 2021
Lagoons interspersed within wetlands are expected to increase the residence time of the flow in the system which, in turn, will lead to enhanced pollutant removal thus ensuring a good ecological status of the ecosystem.
TERESA Serra, Estel Font, Marianna Soler   +2 more
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Stratospheric mean residence time and mean age on the tropopause: Connections and implications for observational constraints [PDF]

Journal of Geophysical Research, 2012
Stratospheric mean residence time  and mean age on the tropopause ΓΩ are shown to measure physically distinct aspects of stratospheric transport. Both ΓΩ and  are mean transit times through the stratosphere of air that enters through tropopause region Ω
Mark Holzer, Clara Orbe, François W Primeau   +2 more
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Comments on mean residence time determination

Journal of Pharmacokinetics and Biopharmaceutics, 1985
In a recent paper, D. O. Chanter challenged the applicability of the use of statistical moments in estimating mean residence time and proposed an alternative approach. Errors in that paper are pointed out which involve the improper equating of whole-body amount of drug with plasma amount of drug in a kinetic system.
E M, Landaw, D, Katz
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The mean oceanic residence time

Marine Chemistry, 1982
Abstract In this note the significance of heat of hydration and electronegativity in the study of oceanic residence times of elements is discussed.
Chen-Ping Chang, Lian-Sen Liu, Chen-Tung Chen   +2 more
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