Results 131 to 140 of about 294,527 (276)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Design, rationale, and baseline characteristics of the dapagliflozin in haemodialysis (DAPA-HD) trial. [PDF]

ESC Heart Fail
Zelniker TA, Paschen C, Mann C, Eigner M, Hafner-Gießauf H, Kletzmayr J, Lorenz M, Ludvik B, Stulnig T, Waller I, Werzowa J, Hödlmoser S, Hengstenberg C, Oberbauer R, Hecking M.   +14 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PrP turnover in vivo and the time to effect of prion disease therapeutics. [PDF]

PLoS Pathog
Corridon TL, O'Moore J, Seerley A, Sprague DA, Lian Y, Laversenne V, Noble B, Kamath NG, Serack FE, Shaikh AB, Erickson B, Braun C, DeSouza-Lenz K, Howard M, Chan N, Jackson WS, Reidenbach AG, Cabin DE, Vallabh SM, Grindeland Panter A, Oberbeck N, Zhao HT, Minikel EV.   +22 more
europepmc   +1 more source

Beyesian Statistical Inference on Mean Residual Life Function

, 2016
The mean residual function is very important in survival analysis, where lifetime distributions that model the time to a particular event are studied. This includes machine failure times, service and repair times, and event duration times, in general. The mean residual function provides the expected remaining life of lifetime distributions given that ...
openaire  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Integrating physical modeling with artificial intelligence for predicting fish survival zones in polluted rivers to maintain a sustainable aquaculture industry. [PDF]

Sci Rep
El-Sattar HKA, Elshambakey M, Saleh A, Antar S.   +3 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Rate of decline in residual kidney function and cognitive impairment in incident haemodialysis patients: A prospective, longitudinal analysis of the BISTRO trial cohort. [PDF]

PLoS One
Rosenberg KL, Dasgupta I, Nitsch D, Belcher J, Farrington K, Davies S.   +5 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source