Results 141 to 150 of about 294,527 (276)

Impact of Single-Inhaler Triple Therapy FF/UMEC/VI on Disease Stability in COPD: A Real-World 12-Month Analysis. [PDF]

Pulm Ther
Lupia C, Pastore D, Giacalone A, Marrelli F, Novelli L, Riccelli D, Maglio A, Armentaro G, Sciacqua A, Vatrella A, Pelaia G, Pelaia C.   +11 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Impact of Small-for-Gestational-Age on Pulmonary Function in Infancy, a Retrospective Cohort Study. [PDF]

Pediatr Pulmonol
Hevroni A, Wetzler NJ, Gileles-Hillel A, Cohen-Cymberknoh M, Boursheh LS, Breuer O.   +5 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Factors associated with the life-space assessment in community-dwelling older adults requiring support. [PDF]

J Phys Ther Sci
Hosaka K, Uchinoura M, Otao H, Shibata H.   +3 more
europepmc   +1 more source

Estimation of survival and mean residual life functions from dependent random censored data

, 2014
R S Muradov
openalex   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Associations between productive engagement and intrinsic capacity and their longitudinal effects on subjective well-being among older adults: a cross-lagged panel mediation analysis. [PDF]

J Nutr Health Aging
Jiang Y, Fu J, Zhou C, Yue X, Liu Y.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Primary Open-Angle Glaucoma With Improved Visual Outcomes Following Audio-Luminous Biofeedback Training: A Case Report. [PDF]

Am J Case Rep
Nsour G, Andreoli AJ, Markowitz S, Daibert-Nido M.   +3 more
europepmc   +1 more source