Results 51 to 60 of about 51,887 (242)

The Cambanis family of bivariate distributions: Properties and applications

open access: yesStatistica, 2016
The Cambanis family of bivariate distributions was introduced as a generalization of the Farlie-Gumbel-Morgenstern system. The present work is an attempt to investigate the distributional characteristics and applications of the family.
N. Unnikrishnan Nair   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Medical application with an extended Ailamujia inverted Weibull model: Properties, estimation and simulation

open access: yesAlexandria Engineering Journal
In this article, we propose a new lifetime model called Kavya-Manoharan Ailanujia inverted Weibull distribution, which is obtained from the Kavya-Manoharan (KM) transformation family and Ailanujia inverted Weibull distribution.
Azedine Grine
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Constraint-Adjusted Nonparametric Inference for Residual-Life Functionals Under Stochastic Precedence

open access: yesMathematics
Nonparametric inference for residual-life functionals is a fundamental problem in mathematical statistics, reliability theory, and survival analysis, particularly in studies with limited sample sizes where empirical plug-in estimators may exhibit ...
Abdulmajeed A. R. Alharbi
doaj   +1 more source

On weighted exponential-Gompertz distribution: properties and application

open access: yesJournal of Taibah University for Science, 2019
In this paper, we introduce a new distribution generated by an integral transform of the probability density function of the weighted exponential distribution. This distribution is called the weighted exponential-Gompertz (WE-G). Its hazard rate function
Ahmed M. T. Abd El-Bar, I. E. Ragab
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Actuarial and various entropy measures for a new extended log Kumaraswamy model: Properties and applications

open access: yesAlexandria Engineering Journal
This article introduces a novel extension of the log Kumaraswamy distribution, termed Marshall Olkin log Kumaraswamy (MOLkw). The mathematical and statistical characteristics of the suggested distribution are constructed, encompassing explicit ...
Naif Alotaibi
doaj   +1 more source

A Two-Parameter Weighted Rama Distribution with Properties and Application

open access: yesUniversal Journal of Mathematics and Applications, 2019
In this paper, a two-parameter weighted Rama distribution which includes one parameter Rama distribution introduced by Shanker [1] has been proposed for modelling real lifetime data.
Tesfalem Eyob, Rama Shanker
doaj   +1 more source

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