Results 261 to 270 of about 4,922,677 (379)

Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias

Advanced Science, EarlyView.
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei, Wuqiang Wen, Wenjun Zhang, Shujing Zhang, Ting Sun, Guiming Li, Jing Zhang, Shuang Qi, Jie Zhou, Bing Li, Yunshuo Zhao, Xiaotong Chen, Bowen Li, Yiying Xue, Wang Lu, Yanli Sun, Jingyao Wang, Hengyue Shan, Shengzhe Zhang, Yushan Huang, Yisa Chen, Wenchao Wang, Qingsong Liu, Wenchao Lu, Li Tan, Yi Ding, Jianfei Fu, Jun Long, Lei Zhang, Baobing Zhao, Aibin Liang, Baishan Jiang, Jing Yang   +32 more
wiley   +1 more source

Reversion of heme-dependent metronidazole resistance in <i>Clostridioides difficile</i>. [PDF]

Microbiol Spectr
Louis L, Ramzan F, Martin DD, Olaitan AO.   +3 more
europepmc   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Particle-Filled Emulsion Drops Show Flow-Induced Partial Coalescence, but Only Transiently. [PDF]

Ind Eng Chem Res
Vaswani J, Velankar SS.
europepmc   +1 more source

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

Advanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang, Zining Liu, Mengjun Li, Judun Zheng, Ruilin Zhang, Ke Liu, Xiaoxue Li, Shaoying Wen, Jingze Yu, Meijia Pan, Fengbo Ma, Kun Zhou, Zheng Zhao, Chenguang Shen, Yuhui Liao   +14 more
wiley   +1 more source

Impact of CCD Inhibition on Semi-Quantitative Multiple Allergen Simultaneous Test. [PDF]

Diagnostics (Basel)
Lee H, Song K, Kim J, Koo J, Kim J.
europepmc   +1 more source

Using Mean Reversion as a Measure of Persistence

, 2005
Daniel A. Dias, Carlos Robalo Marques
openalex   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

Leveraging hepatitis B vaccination to consolidate functional cure: reigniting the humoral axis in chronic HBV infection. [PDF]

Emerg Microbes Infect
Ren S, Zheng S, Chen X.
europepmc   +1 more source

A Sub‐1 Nm Cluster Chains‐enhanced Poly(ethylene oxide) Electrolyte for an All‐solid‐State Lithium Metal Battery with a Long Cycling Lifespan

Advanced Science, EarlyView.
Sub‐1 nm inorganic cluster chain with cation vacancies optimize PEO electrolytes by eliminating Li+ migration barriers and constructing 3D ion transport networks, while in situ c‐AFM reveals dynamic transport mechanisms, enabling high‐performance all‐solid‐state batteries. Abstract Flexible composite polymer electrolytes (CPEs) are promising candidates
Shanshan Song, Fei He, Yijun Gao, Yumeng Zhang, Junming Zhang, Tongjiao Yin, Qiqi Sun, Zhiliang Liu, Piaoping Yang   +8 more
wiley   +1 more source