FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Experiments in monthly mean simulation of the atmosphere with a coarse-mesh general circulation model [PDF]
The Hansen atmospheric model was used to compute five monthly forecasts (October 1976 through February 1977). The comparison is based on an energetics analysis, meridional and vertical profiles, error statistics, and prognostic and observed mean maps ...
Lutz, R. J., Spar, J.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Evaluation of W0 in Canada using tide gauges and GOCE gravity field models
Journal of Geodetic Science, 2012 The existing Canadian Geodetic Vertical Datum of 1928 (CGVD28) does not meet the needs of the modern user in terms of accuracy and accessibility.
Hayden T. +3 more
doaj +1 more source
Reconstructing past global mean sea levels
, 2023 Invited presentation at the "SP-Heritage" project meeting, San Remo, Italy (2-3 March 2023)
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Optical Turbulence Measurements and Models for Mount John University Observatory
, 2010 Site measurements were collected at Mount John University Observatory in 2005 and 2007 using a purpose-built scintillation detection and ranging system.
Avila +17 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Pengamatan Pasang Surut untuk Penentuan Datum Ketinggian di Pantai Desa Parak, Kecamatan Bonto Matene, Kabupaten Selayar, Provinsi Sulawesi Selatan [PDF]
, 2016 Height of a point on land is determined by the position of sea level Average ( Mean Sea Level) . This paper investigates the Bench Mark local elevation measurements to Mean Sea Level tidal observations for 15 days at the village of Parak , District Bonto
Muhiddin, A. H. (Amir) +1 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source