Results 41 to 50 of about 248,461 (262)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Investigation of the efficiency of support vector machine in predicting changes in water quality parameters (Case study: Choghakhor International Wetland) [PDF]

بوم‌شناسی آبزیان, 2020
Inland waters, such as wetlands, are considered to be sensitive ecosystems, and sustainable productivity can only be achieved by adopting an appropriate environmental approach.
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doaj  

Single-tone frequency estimation based on reformed covariance for half-length autocorrelation

Metrology and Measurement Systems, 2020
This paper presents a new simple and accurate frequency estimator of a sinusoidal signal based on the signal autocorrelation function (ACF). Such an estimator was termed as the reformed covariance for half-length autocorrelation (RC-HLA).
Sergiusz Sienkowski, Mariusz Krajewski
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

On the Statistical Analysis of the Harmonic Signal Autocorrelation Function

International Journal of Applied Mathematics and Computer Science, 2021
The article presents new tools for investigating the statistical properties of the harmonic signal autocorrelation function (ACF). These tools enable identification of the ACF estimator errors in measurements in which the triggering of the measurements ...
Sienkowski Sergiusz, Krajewski Mariusz
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Estimation of finite population variance using auxiliary information in sample surveys

Statistica, 2014
This paper addresses the problem of estimating the finite population variance using auxiliary information in sample surveys. Motivated by (Singh and Vishwakarma, 2009) some estimators of finite population variance have been suggested along with their ...
Housila P. Singh, Alok K. Singh, Ramkrishna S. Solanki   +2 more
doaj   +1 more source

Perceptual Fidelity Aware Mean Squared Error [PDF]

2013 IEEE International Conference on Computer Vision, 2013
How to measure the perceptual quality of natural images is an important problem in low level vision. It is known that the Mean Squared Error (MSE) is not an effective index to describe the perceptual fidelity of images. Numerous perceptual fidelity indices have been developed, while the representatives include the Structural SIMilarity (SSIM) index and
Wufeng Xue, Xuanqin Mou, Lei Zhang 0006, Xiangchu Feng   +3 more
openaire   +1 more source