Results 141 to 150 of about 1,446,763 (330)
Engineering ReportsThis work proposes a new continuous input current cubic gain buck‐boost converter with a simple structure and reduced components. The converter has minimal components consisting of a twin‐switch configuration with a broad range of duty‐cycle operations ...
Ifham H. Malick +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
On a method for mending time to failure distributions [PDF]
Many software reliability growth models assume that the time to next failure may be infinite; i.e., there is a chance that no failure will occur at all. For most software products this is too good to be true even after the testing phase.
Trivedi, Kishor S., Grottke, Michael
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Smooth Breaks and Nonlinear Mean Reversion: Post-Bretton Woods Real Exchange Rates
The recent literature on Purchasing Power Parity (PPP) has emphasized the role of two phenomena that may lead to the rejection of the PPP hypothesis: structural breaks and nonlinear adjustment induced by transaction costs.
Dimitris, Christopoulos +1 more
core
Integrated Degradation Models in R Using iDEMO
Journal of Statistical Software, 2012 Degradation models are widely used to assess the lifetime information for highly reliable products with quality characteristics whose degradation over time can be related to reliability.
Chien-Yu Peng, Ya-Shan Cheng
doaj
Varaince reduction in mean time to failure simulations
Winter simulation conference : proceedings, 1988 Penvez Shahabuddin +6 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source