Results 51 to 60 of about 1,338,716 (305)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Maintenance Optimization of High Voltage Substation Model

Advances in Electrical and Electronic Engineering, 2008
The real system from practice is selected for optimization purpose in this paper. We describe the real scheme of a high voltage (HV) substation in different work states. Model scheme of the HV substation 22 kV is demonstrated within the paper. The scheme
Radim Bris, Jan Gala
doaj  

Return to Play After Isolated Meniscal Repairs in Athletes: A Systematic Review

Orthopaedic Journal of Sports Medicine, 2020
Background: Meniscal tears are a common knee injury. Isolated meniscal tears are less common; however, unaddressed tears can be troublesome, particularly for athletes.
Erica R. Blanchard BS, Christopher J. Hadley BS, Eric D. Wicks MD, William Emper MD, Steven B. Cohen MD   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Enhancing Reliability Indices in Power Distribution Grids Through the Optimal Placement of Redundant Lines Using a Teaching–Learning-Based Optimization Approach

Energies
Given the pressing need to strengthen operational reliability in electrical distribution networks, this study proposes an optimization methodology based on the Teaching–Learning-Based Optimization (TLBO) algorithm for the strategic location of redundant ...
Johao Jiménez, Diego Carrión, Manuel Jaramillo   +2 more
doaj   +1 more source

Achilles Tendon Repair With Modified Giftbox Technique Using Nonabsorbable Suture Loops

Video Journal of Sports Medicine, 2021
Background: Achilles tendon ruptures occur most commonly in male individuals aged between 30 and 60 years. Indications: Surgical options for treatment of acute midsubstance Achilles tendon ruptures in the athletically active population include open, mini-
Timothy L. Miller MD, Eric Welder MD
doaj   +1 more source

Optimizing Scrubbing by Netlist Analysis for FPGA Configuration Bit Classification and Floorplanning

, 2017
Existing scrubbing techniques for SEU mitigation on FPGAs do not guarantee an error-free operation after SEU recovering if the affected configuration bits do belong to feedback loops of the implemented circuits.
Schmidt, Bernhard, Teich, Jürgen, Ziener, Daniel, Zöllner, Christian   +3 more
core   +2 more sources

Association between the c.*229C>T polymorphism of the topoisomerase IIb binding protein 1 (TopBP1) gene and breast cancer [PDF]

, 2012
Topoisomerase IIb binding protein 1 (TopBP1) is involved in cell survival, DNA replication, DNA damage repair and cell cycle checkpoint control. The biological function of TopBP1 and its close relation with BRCA1 prompted us to investigate whether ...
A Jemal, A Yokoyama, Agnieszka Szymczyk, Anna Krześlak, Beata Smolarz, BF Pachkowski, CW Elston, D Fanale, DP Bartel, E Forma, Ewa Brzeziańska, Ewa Forma, G Corrao, G Papagregoriou, Grażyna Chwatko, Hanna Romanowicz-Makowska, ID Fleming, J Shen, JNM Glover, JS Morris, JS Morris, K Liu, K Metsola, LE Mechanic, M Sokka, Magdalena Bryś, MC Rodriguez, P Reynolds, Paweł Jóźwiak, PJ Brooks, RE Shore, S Chatterjee, S Peng, SM Karppinen, SS Coughlin, Waldemar Różański, X Liu, Y Jeon, Y Xu   +38 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Failure Rates After Anterior Cruciate Ligament Repair With Suture Tape Augmentation in an Active-Duty Military Population

Orthopaedic Journal of Sports Medicine, 2023
Background: Anterior cruciate ligament (ACL) repair had previously been considered the standard of care for a ruptured ACL; however, ACL reconstruction has became the standard of care because of poor midterm outcomes after ACL repair.
Christian A. Cruz MD, Brian J. Mannino MD, Connor B. Venrick MD, Rebecca N. Miles BS, David R. Peterson MD, Liang Zhou MD, Kyong S. Min MD, Craig R. Bottoni MD   +7 more
doaj   +1 more source