Results 51 to 60 of about 4,447,211 (268)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Quantum-enhanced mean value estimation via adaptive measurement [PDF]

Quantum
Quantum-enhanced (i.e., higher performance by quantum effects than any classical methods) mean value estimation of observables is a fundamental task in various quantum technologies; in particular, it is an essential subroutine in quantum computing ...
Kaito Wada, Kazuma Fukuchi, Naoki Yamamoto   +2 more
doaj   +1 more source

Cone Beam Computed Tomography-An Effective Tool in Detecting Caries Under Fixed Dental Prostheses [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Caries under restorations is the most common reason for re-treatment and replacement in restorative failures. To avoid failures of fixed dental prostheses, it is important to diagnose caries under it earlier.
Priyanka Ramesh Vedpathak, Shailesh Madhukar Gondivkar, Ajay Ramesh Bhoosreddy, Karan Rajendra Shah, Gaurav Ravishankar Verma, Gayatri Praveen Mehrotra, Ashwini Chandrakant Nerkar   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

On Generalized Flett's Mean Value Theorem

International Journal of Mathematics and Mathematical Sciences, 2012
We present a new proof of generalized Flett's mean value theorem due to Pawlikowska (from 1999) using only the original Flett's mean value theorem. Also, a Trahan-type condition is established in general case.
Jana Molnárová
doaj   +1 more source

MEAN VALUES AND MEAN-CONVOLUTION PRODUCTS

Kyushu Journal of Mathematics, 1996
This paper is concerned with mean values and mean convolution products for bounded measurable functions on \(R^m\). These are computed with respect to a weight function \(h(x)\), which is nonnegative and has the unit mass. The limit \(M(h,f)\) of \((1/L^m)I[h((x-y)/L)f(y)]\), as \(L\) goes to infinity, when it exists independently of \(x\), is the mean
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Some statistical tools on intuitionistic fuzzy threshold hypergraphs [PDF]

Big Data and Computing Visions
This paper explores the intersection of intuitionistic fuzzy threshold numbers, variables, and statistical measures within the domain of Intuitionistic Fuzzy Threshold Hypergraphs (IFTHGs).
Nandhini Chandrasekar, R Keerthika
doaj   +1 more source