Results 61 to 70 of about 4,447,211 (268)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On mean value properties involving a logarithm-type weight [PDF]
Two new assertions characterizing analytically disks in the Euclidean plane $\mathbb{R}^2$ are proved. Weighted mean value property of positive solutions to the Helmholtz and modified Helmholtz equations are used for this purpose; the weight has a ...
Nikolay Kuznetsov
doaj +1 more source
On some mean value theorem via covering argument
We show how the full covering argument can be used to prove some type of Cauchy mean value theorem.
Sokołowski Dariusz
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Theory of random measurement errors: concepts, uses, and misuses
We present an overview of the theory of random measurement errors, focusing on the underlying concepts rather than on a strict mathematical formulation. Although the related literature is extensive, one can frequently encounter partly or completely wrong
Zauner Branimir +7 more
doaj +1 more source
On Some Intermediate Mean Values
We give a necessary and sufficient mean condition for the quotient of two Jensen functionals and define a new class $Λ_{f,g}(a, b)$ of mean values where $f, g$ are continuously differentiable convex functions satisfying the relation $f"(t)=t g"(t), t\in \Bbb R^+$.
openaire +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

