Results 111 to 120 of about 16,092,020 (251)

Generating Functions for the Mean Value of a Function on a Sphere and Its Associated Ball in

open access: yesJournal of Inequalities and Applications, 2008
We define two functions which determine the properties and the representation of the mean value of a function on a ball and on its associated sphere. Using these two functions, we obtain Pizzetti's formula in as well as a similar formula for the mean ...
Toma Antonela
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Lp-functions satisfying the mean value property on homogeneous spaces

open access: yes, 1994
It is proved that on certain kinds of homogeneous spaces, the only Lp-function, 1≤ p < ∞, satisfying the mean value property is the zero ...
Sitaram, A., Willis, G. A.
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Assessment of renal perfusion and oxygenation in transplant donor-recipient pairs using arterial spin labelling (ASL) and blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI)

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine
Objectives To evaluate the role of arterial spin labelling (ASL) and blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) in assessment of perfusion and oxygenation in kidney transplant donor-recipient pairs.
Mostafa A. Zakaria   +3 more
doaj   +1 more source

Geometric Representation of the Mean-Variance-Skewness Portfolio Frontier Based upon the Shortage Function [PDF]

open access: yes
The literature suggests that investors prefer portfolios based on mean, variance and skewness rather than portfolios based on mean-variance (MV) criteria solely.
Kristiaan Kerstens   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Interaction of 5-HTTLPR and SLE disease status on resting-state brain function

open access: yesArthritis Research & Therapy
Background Neuropsychiatric involvement in systemic lupus erythematosus (SLE) is a common clinical manifestation. In SLE patients, cerebral function is a more sensitive predictor of central nervous system damage, and abnormalities in cerebral function ...
Lihua Ma   +8 more
doaj   +1 more source

Quasi-Mean Value Theorems for Symmetrically Differentiable Functions

open access: yes, 2012
[[abstract]]In this paper, we give a survey of results related the various quasimean value theorems for symmetrically differentiable functions and present some new results.
Prasanna K. Sahoo
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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