Results 61 to 70 of about 472,341 (252)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Genetic Variability, Heritability, and Genetic Advance Estimates in Garlic (Allium sativum) from the Gamo Highlands of Southern Ethiopia

International Journal of Agronomy, 2021
Genetic variability is the fundamental requirement for any plant breeding program to develop a superior cultivar. This study aimed to estimate the genetic variability and determine the correlation between the various quantitative characteristics of ...
Azene Tesfaye
doaj   +1 more source

Soil water repellency changes with depth and relationship to physical properties within wettable and repellent soil profiles

Journal of Hydrology and Hydromechanics, 2017
This study explored the effect of soil water repellency (SWR) on soil hydrophysical properties with depth. Soils were sampled from two distinctly wettable and water repellent soil profiles at depth increments from 0-60 cm. The soils were selected because
Sepehrnia Nasrollah, Hajabbasi Mohammad Ali, Afyuni Majid, Lichner Ľubomír   +3 more
doaj   +1 more source

Mean weight diameter and water holding capacity of aggregates under contrasting soil tillage systems

, 2021
Aggregate stability and organic matter are key attributes in minimizing detrimental impacts of agricultural practices and sustaining soil and environmental quality. Long-term (2006-2014)effects of six different tillage systems on aggregate size distribution and water holding capacitywere investigated in a soil contained approximately 50% clay.
Acar, Mert, Çelik, İsmail, Günal, Hikmet, Sarıyev, Alhan   +3 more
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Restoration of the structure and soil protection role of no-till in chernozems and chestnuts soils of the Stavropol Territory

Бюллетень Почвенного института им. В.В. Докучаева
The results of research on the example of southern chernozem and chestnut soil are presented. Long-term use of plowing with rotation of the soil layer and the use of fallows leads to a critical state of the soil in terms of the content of aggregates ...
S. A. Yudin, N. R. Ermolaev, V. P. Belobrov, V. K. Dridiger, R. G. Gadzhiumarov, N. V. Yaroslavtseva, I. A. Nadutkin   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source