Results 81 to 90 of about 1,753,183 (313)
Phenomenological description of the process of producing meanings by the method of guided drawing
Тhe work gives a phenomenological description of the process of arising of the meanings that are significant for the current moment in the person's life and activity through the Guided Drawing method; the structure and dynamics of the process are ...
Buyakas T.M., Tankova O.A.
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
[Darwinism and the meaning of "meaning"].
The problem of the meaning of life is herewith contemplated from a Darwinian perspective. It is argued how factors such as existential depression, the concern about the meaning of ‘meaning’, the problem of evil, death as the end of our personal identity, happiness as an unachievable goal, etc. may well have an adaptive dimension ‘controlled’ neither by
openaire +2 more sources
Expressivism, Inferentialism and the Theory of Meaning [PDF]
One’s account of the meaning of ethical sentences should fit – roughly, as part to whole – with one’s account of the meaning of sentences in general. When we ask, though, where one widely discussed account of the meaning of ethical sentences fits with ...
Chrisman, Matthew; id_orcid +1 more
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Based on detailed studies of the past of the agrarian thought of the world (evolution of agro-innovation), and within it, the relationship of man and seed, the author has selected key data for Table 1.
Mirić Mladen
doaj
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Bu çalışmada, sosyal bilimlerde 1950’li yıllardan başlayarak dilbilimden sosyolojiye, psikolojiden etnolojiye kadar birçok alanda kendinden söz ettiren yapısalcılık ve yapısalcılığın en önemli isimlerinden biri olan Levi-Strauss’un yaklaşımıincelenmiştir.
Ahmet Koyuncu
doaj

