Results 91 to 100 of about 1,753,183 (313)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Urban Spaces to (and of) Play: An Exploratory Study in the City of Salvador (BA)
Psicologia, 2009 With the growth of large urban centers, public spaces have become places considered unsuitable and dangerous for children and their recreational activities.
Gabriela Souza Cotrim +3 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Family and meaning: examining the four needs for meaning as mediators
, 2012 In a series of three studies we investigated the relationship between family and meaning and tested whether Baumeister’s (1991) four needs for meaning (purpose, values, efficacy, and self-worth) mediated this relationship.
Stillman, Tyler F. +3 more
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Giving meaning to sport involvement in managerial work
, 2009 I use a discursive analytical approach to explore ways in which senior managerial men working in nonprofit organizations understand the contribution, if any, of their own sport history to their work skills, how this may vary by organizational contexts ...
Knoppers, A.E. +5 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Content and Meaning Constitutive Inferences
Studia Semiotyczne, 2019 DOI: http://doi.org/10.26333/sts.xxxiii1.03 A priori theories of justification of logic based on meaning often lead to trouble, in particular to issues concerning circularity. First, I present Boghossian’s a priori view.
Maria Dolores Garcia-Arnaldos
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Challenges of Technical Translation: Case Study [PDF]
Ovidius University Annals: Economic Sciences Series, 2016 The aim of this paper is to provide an analysis of the textile industry vocabulary, in order tohighlight the variety of the terms used to describe the respective field and to emphasize thedifficulties that hinder the translation of a specialized text ...
Alina Buzarna-Tihenea (Galbeaza) +1 more
doaj
User-centred websites: The (ir)relevance of age
, 2009 Do elderly people really navigate websites in a different way than younger people do? Or are the differences within this group (such as those due to gender, education, computer experience and cultural background) bigger then differences between younger ...
LSG Management of Meaning (MOM) +1 more
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