Results 111 to 120 of about 1,753,183 (313)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Boletín de Filología, 2010 La definición de variables morfosintácticas suele basarse en la identidad de sus variantes en el nivel semántico descriptivo; no obstante, a menudo existen diferencias en los planos del discurso y la cognición. Así, las formas reflexivas del paradigma de
Miguel Ángel Aijón Oliva
doaj
Grammar, Ontology, and the Unity of Meaning [PDF]
, 2013 Words have meaning. Sentences also have meaning, but their meaning is different in kind from any collection of the meanings of the words they contain. I discuss two puzzles related to this difference.
REICHARD, ULRICH
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Meaning holism and de re ascription
, 2008 According to inferential role semantics, for an expression to have a meaning is for it to have a role in inference. It is widely recognised that any such theory seems to face a communication problem.
Whiting, Daniel, Daniel Whiting
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Meaning in Music Framed: The Four ‘Eff’ Processes (Fit, Affiliation, Facilitation, and Fluency)
Behavioral SciencesMusic can evoke powerful, positive, and meaningful experiences, but how does its potential to evoke such experiences come about? Listening to the music itself is critical, but referents (the thoughts, ideas, events, and affects associated with the music)
Emery Schubert, Anthony Chmiel
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Reconstructing meaning after trauma : theory, research, and practice /
Includes bibliographical references and index.Online resource; title from pdf title page (EBSCO, viewed January 31, 2017).Foundations of Meaning and Trauma.
Altmaier, Elizabeth M.,editor.
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