Results 151 to 160 of about 674,697 (350)
Thinking of You: The Interpersonal Work Meaningfulness Model
A growing literature indicates that people are desired to experience a sense of positive work meaning. Although the topic on the antecedents of work meaningfulness is relatively well studied, we know comparatively little about how other people affect an ...
Hu, Jing
core +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Conceptualizing Meaningful Experiences
Despite increased interest in experience and experience design in hospitality, tourism, and leisure, the field remains emergent. For experience design to mature in research and practice, clear consensus conceptualization of key constructs, like memorable, meaningful, and transformative experiences, is needed. While existing research identifies emotions
Marcel Bastiaansen, Mat D. Duerden
openaire +3 more sources
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
On the Association between the Pleasantness and Meaningfulness of Words
To study the associations between the pleasantness and meaningfulness of words of four classes (pleasant and concrete, unpleasant and concrete, pleasant and abstract, unpleasant and abstract), we presented a 20-word list for each class to 184 subjects ...
Alfredo Campos
core +1 more source
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Reflections on Meaningfulness and its Social Relevance
Philosophers who write about the meaning of life are few nowadays. Thesubject has lost its attractiveness. Perceived from a viewpoint of logical positivism or language philosophy, the whole issue of meaningfulness seems rather pointless.
Nicole Note
core
We are concerned with the definition of means or averaging operators, i.e., aggregators M(x1,…,xi,…,xm) where xi ϵ R represent measures on the reals corresponding to a given type of scale (ordinal, interval or ratio scale). The adequate mean which varies
János Fodor +3 more
core +1 more source

