Results 71 to 80 of about 6,711,621 (313)

Biographical Material - Jim Means

open access: yes, 1949
Collected by Merlin Mitchell Transcribed by Kyle Perrin Reel 9 Items 1-5 Jim Means (fiddle) Goshen, Ark. Biographical Material And Fi dle Pieces November 9, 1949 Means •• I was raised back in the mountains and my family were more or less backward but ...
Means, Jim
core  

A new look at means on topological spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
We use methods of algebraic topology to study when a connected topological space admits an n-mean map.
Peter Hilton
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On Some Inequalities of Symmetric Means and Mixed Means

open access: yes, 2005
We improve some inequalities involving the symmetric means.
Gao, Peng
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Land Grant Application- Means, Thomas (Freeport)

open access: yes, 2017
Land grant application submitted to the Maine Land Office for Thomas Means for service in the Revolutionary War.https://digitalmaine.com/revolutionary_war_me_land_office/1634/thumbnail ...
Means, Thomas
core   +1 more source

Calcium/Calmodulin-Dependent ProteinKinase Kinase 2: Roles in Signaling and Pathophysiology

open access: yes, 2012
minireview on functions of CaMKK2 and its potential as a target for therapeutic ...
Anthony R. Means, RACIOPPI, LUIGI
core   +1 more source

Home - About - Disclaimer - Privacy