Results 51 to 60 of about 124,043 (278)
Advanced Science, EarlyView.Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang +10 more
wiley +1 more source
Public Health Nursing, Volume 40, Issue 1, Page 90-96, January/February 2023., 2023 Abstract COVID‐19 vaccine hesitancy poses serious challenges in achieving adequate vaccine coverage in the general population. While most studies on vaccine hesitance determinants during the COVID‐19 pandemic were quantitative, qualitative research on the reasons for vaccine resistance is still lacking.
Cecilia Perrone +6 more
wiley +1 more source
Advanced Science, EarlyView.This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo +10 more
wiley +1 more source
The measles epidemic trend over the past 30 years in a central district in Shanghai, China.
PLoS ONE, 2017 BackgroundMeasles vaccination over the past 50 years has greatly reduced the incidence of measles. However, measles among migrants and the resulting changes in epidemiological characteristics have brought new challenges to the elimination of measles.
Jie Gao +4 more
doaj +1 more source
Estimation of reproduction numbers in real time: Conceptual and statistical challenges
Journal of the Royal Statistical Society: Series A (Statistics in Society), Volume 185, Issue S1, Page S112-S130, November 2022., 2022 Abstract The reproduction number R$$ R $$ has been a central metric of the COVID‐19 pandemic response, published weekly by the UK government and regularly reported in the media. Here, we provide a formal definition and discuss the advantages and most common misconceptions around this quantity.
Lorenzo Pellis +13 more
wiley +1 more source
Estimating efficacy of measles supplementary immunization activities via discrete-time modeling of disease incidence time series [PDF]
arXiv, 2020 Measles is a significant source of global disease burden and child mortality. Measles vaccination through routine immunization (RI) programs in high-burden settings remains a challenge due to poor health care infrastructure and access. Supplementary immunization activities (SIA) in the form of vaccination campaigns are therefore implemented to prevent ...
arxiv
Cytometry Part A, EarlyView.ABSTRACT T cell responses are rarely measured in large‐scale human vaccine studies due to the sample volumes required, as well as the logistical, technical, and financial challenges associated with available assays. Fluorescent cell barcoding has been proposed in other contexts to allow for more high‐throughput flow cytometry‐based assays.
Janna R. Shapiro +3 more
wiley +1 more source
Primate Erythroparvovirus 1 Infection in Patients with Hematological Disorders
Pathogens, 2022 Primate erythroparvovirus 1, commonly referred to as Parvovirus B19 (B19V), is a DNA virus that normally results in a mild childhood infection called “erythema infectiosum”.
Stefka Krumova +5 more
doaj +1 more source
Likelihood-based estimation and prediction for a measles outbreak in Samoa [PDF]
arXiv, 2021 Prediction of the progression of an infectious disease outbreak is important for planning and coordinating a response. Differential equations are often used to model an epidemic outbreak's behaviour but are challenging to parameterise. Furthermore, these models can suffer from misspecification, which biases predictions and parameter estimates ...
arxiv
PLoS ONE, 2022 The Democratic Republic of the Congo (DRC) has a high measles incidence despite elimination efforts and has yet to introduce rubella vaccine. We evaluated the performance of a prototype rapid digital microfluidics powered (DMF) enzyme-linked immunoassay (
Alaine K Knipes +29 more
doaj +1 more source