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Measles was an inevitable infection during the human development with substantial degree of morbidity and mortality. The severity of measles virus (MV) infection was largely contained by the development of a live attenuated vaccine that was introduced into the vaccination programs.
de Swart, Rik L. +3 more
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AE Olaitan, EE Ella, JB Ameh Department of Microbiology, Ahmadu Bello University, Zaria, Nigeria Background: Measles remains the leading cause of vaccine-preventable childhood mortality in developing countries, with its greatest incidence in children ...
Olaitan AE, Ella EE, Ameh JB
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Background: Nigeria is one of the countries with a high prevalence of measles outbreak in children under 5 years old, despite a history of vaccination. This study aims to determine the prevalence of anti-measles virus IgM and IgG among children under 5 ...
Adekola, Hafeez Aderinsayo +6 more
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Micromorphological changes in MDCK cells infected with measles virus [PDF]
There are many electron microscopic observations of the cells infected with measles virus (1-6), and all of them appear to be concerned mainly with observation on the inclusion bodies and not any seems to have described the morphology of mature virus ...
Tawara, Jutaro
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Measles virus causes immunogenic cell death in human melanoma [PDF]
NoOncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Russell, S +44 more
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A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
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Monitoring the circulation of the measles virus and studying its genetic diversity is an important component of the measles elimination program. A methodological approach to molecular genetic studies and their interpretation in the measles surveillance ...
Tatiana S. Rubalskaia +4 more
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Epstein-Barr virus but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants. [PDF]
BACKGROUND: Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are persistent herpesviruses that have various immunomodulatory effects on their hosts. Both viruses are usually acquired in infancy in Sub-Saharan Africa, a region where childhood vaccines ...
Ebrima S Touray +84 more
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Measles virus (MeV) is exceptionally contagious and still a major cause of death in child.However, recently significant progress towards the elimination of measles has been made through increased vaccination coverage of measles-containing vaccines. The hemagglutinin (H) protein of MeV interacts with a cellular receptor, and this interaction is the ...
Maino, Tahara, Makoto, Takeda
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Key parameters of measles virus production for oncolytic virotherapy [PDF]
Attenuated measles virus has revealed selective tumor cell killing and is currently tested in clinical trials for the therapy of cancer patients. The amount of infectious particles per dose needed for oncolytic therapy can be more than a million times ...
Salzig, Denise +10 more
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