Results 31 to 40 of about 73,114 (210)

External Quality Assessment for the Detection of Measles Virus by Reverse Transcription-PCR Using Armored RNA. [PDF]

PLoS ONE, 2015
In recent years, nucleic acid tests for detection of measles virus RNA have been widely applied in laboratories belonging to the measles surveillance system of China.
Dong Zhang, Yu Sun, Tingting Jia, Lei Zhang, Guojing Wang, Rui Zhang, Kuo Zhang, Guigao Lin, Jiehong Xie, Lunan Wang, Jinming Li   +10 more
doaj   +1 more source

Results of isolation and genotyping of measles viruses that circulated in 2012–2017 in the Odesa region

Aktualʹnaâ Infektologiâ, 2021
Background. The circulation of different strains of the measles virus is closely related to the region and the incidence rate since circulating strains can change during epidemic outbreaks and in interepidemic periods. According to the WHO, the B3 strain
T.L. Hrydina, V.O. Honcharov, L.S. Kotlik, O.V. Skopenko, O.A. Hruzevsky, K.V. Radkevich   +5 more
doaj   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice

Haematologica, 2014
Novel therapies are needed for pediatric acute lymphoblastic leukemia resistant to conventional therapy. While emerging data suggest leukemias as possible targets of oncolytic attenuated measles virus, it is unknown whether measles virus can eradicate ...
Nike C. Lühl, Felix Zirngibl, Carmen Dorneburg, Jiwu Wei, Meike Dahlhaus, Thomas F.E. Barth, Lüder H. Meyer, Manon Queudeville, Sarah Eckhoff, Klaus-Michael Debatin, Christian Beltinger   +10 more
doaj   +1 more source

Bottom‐Up Ice Growth Geometry Attenuates Shear Stress and Improves the Cryopreservation of Hematopoietic Stem/Progenitor Cells Under Low DMSO Concentrations

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Studies on cell cryopreservation have been limited by the complexity of the freezing process and challenges on controlling ice formation, managing cooling rates, and optimizing cryoprotectant concentrations. The objective of this study is to evaluate the impact of bottom‐up and conventional radial freezing on the viability of mammalian cells ...
Rafaela Ouro Neves, Pedro Sena Rego, Marta H. G. Costa, Isabel Bogalho, Andreia Duarte, Claúdia L. da Silva, Frederico Castelo Ferreira, Vitor Geraldes, Miguel A. Rodrigues   +8 more
wiley   +1 more source

Hepatitis E outbreak in the health district of Bocaranga-Koui, Central African Republic, 2018–2019

BMC Infectious Diseases
Background Hepatitis E virus (HEV) is a major public health disease causing large outbreaks and sporadic cases of acute hepatitis. We investigated an outbreak of HEV infection that occurred in September 2018 in the health district (HD) of Bocaranga-Koui,
Marina Prisca de Marguerite Nombot-Yazenguet, Joël Wilfried Doté, Giscard Wilfried Koyaweda, Philippe Armand Zemingui-Bembete, Benjamin Selekon, Ulrich Vickos, Alexandre Manirakiza, Emmanuel Nakoune, Ionela Gouandjika-Vasilache, Narcisse Patrice Joseph Komas   +9 more
doaj   +1 more source

Performance Evaluation of the VIDAS® Measles IgG Assay and Its Diagnostic Value for Measuring IgG Antibody Avidity in Measles Virus Infection

Viruses, 2016
The objective of this study is primarily to compare the performance of the VIDAS® Measles immunoglobulin (Ig)G assay to that of two other serological assays using an immunoassay technique, Enzygnost® Anti-measles Virus/IgG (Siemens) and Measles IgG ...
Julia Dina, Christian Creveuil, Stephanie Gouarin, Florent Viron, Amelie Hebert, Francois Freymuth, Astrid Vabret   +6 more
doaj   +1 more source

Whole genome analysis of hepatitis B virus before and during long-term therapy in chronic infected patients: Molecular characterization, impact on treatment and liver disease progression

Frontiers in Microbiology, 2022
Hepatitis B virus (HBV) infection remains a serious public health concern worldwide despite the availability of an efficient vaccine and the major improvements in antiviral treatments.
Zeineb Belaiba, Zeineb Belaiba, Kaouther Ayouni, Kaouther Ayouni, Mariem Gdoura, Mariem Gdoura, Wafa Kammoun Rebai, Henda Touzi, Amel Sadraoui, Walid Hammemi, Lamia Yacoubi, Salwa Abdelati, Lamine Hamzaoui, Mohamed Msaddak Azzouz, Anissa Chouikha, Anissa Chouikha, Henda Triki, Henda Triki   +17 more
doaj   +1 more source

Detection of measles vaccine virus and measles-specific immunoglobulin M in children vaccinated against measles-mumps-rubella during measles outbreak

Vaccine: X
Information regarding the detection perioid of measles vaccine virus (MeVV) RNA in human nasopharyngeal samples and measles-specific antibodies following measles-mumps-rubella (MMR) vaccination is limited. During contact tracing for a measles outbreak at
Euri Seo, Yun-Jung Chang, Jae Woo Chung, Yoon-Seok Chung, Seong Yeon Park   +4 more
doaj   +1 more source