Results 41 to 50 of about 3,363 (306)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Distance Based Entropy Measure of Interval-Valued Intuitionistic Fuzzy Sets and Its Application in Multicriteria Decision Making

Advances in Fuzzy Systems, 2018
Fuzzy entropy means the measurement of fuzziness in a fuzzy set and therefore plays a vital role in solving the fuzzy multicriteria decision making (MCDM) and multicriteria group decision making (MCGDM) problems.
Tabasam Rashid, Shahzad Faizi, Sohail Zafar   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The Fuzzy Adaptation of Probabilistic Risk Indicators [PDF]

Problemi Ekonomiki, 2017
The aim of the article is to develop fuzzy tools for measuring risk based on adaptation of corresponding indicators developed within the methodology of the probability theory.
Kotsyuba Oleksiy S.
doaj  

Segmentation via thresholding methodologies by using measure of fuzziness towards blind navigation [PDF]

, 2006
Blind navigation is specialized research directed towards the development of navigational aid for blind people to minimize assistance from sighted individuals during navigation.
R. Nagarajan, Farrah Wong, Sazali Yaacab, Sazali Yaacob, Wong, Farrah   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Fuzzy Measures and the Entropy of Fuzzy Partitions

Journal of Mathematical Analysis and Applications, 1993
The author defines an entropy of a fuzzy partition and proves some basic properties of it. His aim is to get such properties which are very similar to analogous properties for the entropy of probability measures. Therefore, the consideration must be restricted to bounded-sum-union and bounded-product-intersection of fuzzy sets (only in this case a ...
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Fuzziness index driven fuzzy relaxation algorithm and applications to image processing [PDF]

, 2008
An improved fuzzy relaxation algorithm for image contrast enhancement is introduced, the relationship between the convergence regions and the parameters in the transformations defined by the algorithm is shown, which is essential to the successful ...
Zhou, Shang-Ming, John, Robert, 1955-, Gan, J. Q., Gan, John Q, Zhou, Shang Ming, Xu, L. D., Xu, Lida, John, Robert I, Gan, John Q., John, Robert I.   +9 more
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source